RNF103-CHMP3 readthrough

RNF103-CHMP3
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2XZE, 3FRT, 3FRV, 2GD5
Identifiers
Aliases	RNF103-CHMP3, RNF103-VPS24, RNF103-CHMP3 readthrough, NEDF, hVps24, VPS24, CGI149, CHMP3
External IDs	HomoloGene: 130401 GeneCards: RNF103-CHMP3
Gene location (Human)
Chr.	Chromosome 2 (human)[1]
End	86,721,122 bp[1]
RNA expression pattern
	Top expressed in
	skeletal muscle tissue; ; thymus; ; blood; ; gastrocnemius muscle; ; left ventricle; ; bone marrow; ; sural nerve; ; superior frontal gyrus; ; prefrontal cortex; ; bone marrow cells;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; phosphatidylcholine binding; protein homodimerization activity; ubiquitin-specific protease binding; identical protein binding;
Cellular component	cytoplasm; membrane; plasma membrane; endosome; late endosome membrane; extracellular exosome; ESCRT III complex; cytosol; intracellular anatomical structure; late endosome; cytoplasmic vesicle; multivesicular body;
Biological process	autophagosome maturation; viral life cycle; protein polymerization; multivesicular body assembly; cell cycle; cell division; regulation of mitotic spindle assembly; endosomal transport; regulation of centrosome duplication; apoptotic process; protein heterooligomerization; vacuolar transport; septum digestion after cytokinesis; protein transport; nucleus organization; mitotic metaphase plate congression; multivesicular body sorting pathway; regulation of exosomal secretion; macroautophagy; multivesicular body-lysosome fusion; regulation of early endosome to late endosome transport; transport; viral budding via host ESCRT complex; endosome transport via multivesicular body sorting pathway; late endosome to vacuole transport; midbody abscission;
	Sources:Amigo / QuickGO
Orthologs
	100526767
	n/a
	ENSG00000249884
	n/a
	Q9Y3E7
	n/a
	NM_001198954
	n/a
	NP_001005753; NP_001180446; NP_057163
	n/a
	Wikidata
View/Edit Human

RNF103-CHMP3 readthrough is a protein that in humans is encoded by the RNF103-CHMP3 gene. [3]

Function

This locus represents naturally occurring read-through transcription between the neighboring RNF103 (ring finger protein 103) and CHMP3 (charged multivesicular body protein 3) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product.

References

GRCh38: Ensembl release 89: ENSG00000249884 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: RNF103-CHMP3 readthrough". Retrieved 2017-07-04.

RNF103-CHMP3 readthrough

Function

References

Further reading