ROBO2
Roundabout homolog 2 is a protein that in humans is encoded by the ROBO2 gene.[5][6]
References
- GRCh38: Ensembl release 89: ENSG00000185008 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000052516 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Kidd T, Brose K, Mitchell KJ, Fetter RD, Tessier-Lavigne M, Goodman CS, Tear G (January 1998). "Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors". Cell. 92 (2): 205–215. doi:10.1016/S0092-8674(00)80915-0. PMID 9458045. S2CID 2036419.
- "Entrez Gene: ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila)".
Further reading
- Hauptman G, Reichert MC, Abdal Rhida MA, Evans TA (December 2022). "Characterization of enhancer fragments in Drosophila robo2". Fly. 16 (1): 312–346. doi:10.1080/19336934.2022.2126259. PMC 9559326. PMID 36217698.
- Brose K, Bland KS, Wang KH, Arnott D, Henzel W, Goodman CS, et al. (March 1999). "Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance". Cell. 96 (6): 795–806. doi:10.1016/S0092-8674(00)80590-5. PMID 10102268. S2CID 16301178.
- Nguyen Ba-Charvet KT, Brose K, Marillat V, Kidd T, Goodman CS, Tessier-Lavigne M, et al. (March 1999). "Slit2-Mediated chemorepulsion and collapse of developing forebrain axons". Neuron. 22 (3): 463–473. doi:10.1016/S0896-6273(00)80702-3. PMID 10197527. S2CID 18663762.
- Nagase T, Kikuno R, Nakayama M, Hirosawa M, Ohara O (August 2000). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 7 (4): 273–281. doi:10.1093/dnares/7.4.271. PMID 10997877.
- Nguyen Ba-Charvet KT, Brose K, Ma L, Wang KH, Marillat V, Sotelo C, et al. (June 2001). "Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance". The Journal of Neuroscience. 21 (12): 4281–4289. doi:10.1523/JNEUROSCI.21-12-04281.2001. PMC 6762758. PMID 11404413.
- Marillat V, Cases O, Nguyen-Ba-Charvet KT, Tessier-Lavigne M, Sotelo C, Chédotal A (January 2002). "Spatiotemporal expression patterns of slit and robo genes in the rat brain". The Journal of Comparative Neurology. 442 (2): 130–155. doi:10.1002/cne.10068. PMID 11754167. S2CID 24164570.
- Hivert B, Liu Z, Chuang CY, Doherty P, Sundaresan V (December 2002). "Robo1 and Robo2 are homophilic binding molecules that promote axonal growth". Molecular and Cellular Neurosciences. 21 (4): 534–545. doi:10.1006/mcne.2002.1193. PMID 12504588. S2CID 19664833.
- Grieshammer U, Plump AS, Wang F, Tessier-Lavigne M, Martin GR (May 2004). "SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site". Developmental Cell. 6 (5): 709–717. doi:10.1016/S1534-5807(04)00108-X. PMID 15130495.
- Yue Y, Grossmann B, Galetzka D, Zechner U, Haaf T (December 2006). "Isolation and differential expression of two isoforms of the ROBO2/Robo2 axon guidance receptor gene in humans and mice". Genomics. 88 (6): 772–778. doi:10.1016/j.ygeno.2006.05.011. PMID 16829019.
- Lu W, van Eerde AM, Fan X, Quintero-Rivera F, Kulkarni S, Ferguson H, et al. (April 2007). "Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux". American Journal of Human Genetics. 80 (4): 616–632. doi:10.1086/512735. PMC 1852714. PMID 17357069.
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