Reno 911!: Miami

The film opens outside a building where terrorists are holding hostages and a nuclear bomb. The Reno Sheriff's Department arrives in a helicopter, called in as experts. As the group prepare to deal with the situation, Deputy Travis Junior wakes up and realizes it was a dream; he was sleeping at the wheel and the vehicle he and Lt. Dangle are in crashes.

The film continues with introductory clips of the officers, telling how they became interested in law enforcement, à la COPS. After a scene involving a chicken in the road miscoded as an "armed person on a roof", Dangle tells everyone that they have been invited to the American Police Convention in Miami Beach. On arrival, the group finds they're not on the entrant list. Having nowhere to stay, they rent rooms at a motel that seems to be a hub of illegal activities. After partying most of the night, most of the police officers unsuccessfully attempt to seduce one another at the motel, with the males eventually turning to pleasuring themselves to the shock of the ones outside.

As everyone recovers from their hangovers, Johnson discovers a tattoo on her breast of a mystery man. The team return to the convention to see if their tickets were found, but discover the building has been the subject of a bio-chemical terrorist attack that has quarantined the police inside. The only city official left outside is assistant deputy mayor Jeff Spoder. The head of National Security asks the Reno Sheriffs Department to provide law enforcement for Miami Beach. A high-ranking SWAT agent, Rick "The Condor" Smith, arrives on the scene to give a pep talk, but soon ends up blowing himself up with a grenade he had unpinned during the talk.

The team assume the Miami Sheriff's responsibilities, and respond to several emergency calls including an alligator in a swimming pool; street prostitution that leads to Reno: 911 regular Terry who is in town to record an album; and a dead beached whale, which they eventually remove by blowing it up. Jones and Garcia are repeatedly kidnapped by Ethan, a drug lord who tries to act like Tony Montana from Scarface. Spoder fires the team for their incompetence, but as the team brings a cake to apologize to him they discover Spoder in cahoots with Ethan to create a drug empire. Spoder kills Ethan and escapes with the bio-terrorism antidote. The team chase Spoder, who holds them at gunpoint until Jones and Garcia arrive in a Marine helicopter and Spoder surrenders. Lt. Dangle arrests him, but Wiegel, who had been siting in the helicopter, accidentally blows Spoder up.

The antidote is distributed, and the Reno Sheriff's Department are eventually congratulated by their peers for their actions. Dangle accepts a job at the Sheriff's Department at Aspen, who had repeatedly turned him down previously. The remaining team are offered a flight back to Reno by Terry, revealed to have a rich father, on his private jet. Back in Reno, Garcia briefs the team on their day's work. Dangle enters, interrupting the briefing, and explains that Aspen has a zero-tolerance policy forbidding homosexual sheriffs. Dangle continues the briefing, and reveals the group have been invited to a convention at Scotland Yard.

The film stars Thomas Lennon, Ben Garant, Kerri Kenney-Silver, Cedric Yarbrough, Wendi McLendon-Covey, Niecy Nash, Carlos Alazraqui, Paul Rudd, David Koechner, and Mary Birdsong. Certain famed actors make cameos, namely Michael Ian Black (who co-starred with Lennon and Kenney in The State and Viva Variety), Patton Oswalt (Comedian and King of Queens co-star), Danny DeVito (also one of the film's executive producers), Paul Reubens (playing a different character than he plays on the series), Nick Swardson (who appears as his show character "Terry"), and Dwayne Johnson (professional wrestler The Rock). All members of The State appear in the film.

The theme song, "Police and Thieves", is performed by Dave Grohl of the Foo Fighters and subsequent theme song "Do Little Things", is performed by "Changing Faces and Ivan Matias". This is alluded to by Lennon, Garant, and Kenney-Silver on one of the audio commentaries, who say they are not allowed to discuss who performed the song, but say viewers should "Google it" to find the answer.

The film reprises some jokes from the original series for the benefit of first-time viewers, an example being Dangle's explanation for wearing shorts on the job, which was also featured in the first episode of the series.

Writers Garant and Lennon stated in their book Writing Movies for Fun and Profit, that a sequel would not be produced because of insufficient box office returns with the first movie. In the book, a treatment, or extensive outline of what the sequel would have been is included, entitled Reno 911!: SOS. The plot involved the characters of Reno 911! getting stuck on a deserted island with a serial killer on the loose.

• Reno 911!: Miami at IMDb
• Reno 911!: Miami at Box Office Mojo
• Reno 911!: Miami at Rotten Tomatoes
• Reno 911!: Miami at Metacritic