RDH5

11-cis retinol dehydrogenase is an enzyme that in humans is encoded by the RDH5 gene.[5][6][7][8]

RDH5
Identifiers
AliasesRDH5, 9cRDH, HSD17B9, RDH1, SDR9C5, retinol dehydrogenase 5
External IDsOMIM: 601617 MGI: 1201412 HomoloGene: 2179 GeneCards: RDH5
Orthologs
SpeciesHumanMouse
Entrez

5959

19682

Ensembl

ENSG00000135437

ENSMUSG00000025350

UniProt

Q92781

O55240

RefSeq (mRNA)

NM_002905
NM_001199771

NM_134006
NM_001358527

RefSeq (protein)

NP_001186700
NP_002896

NP_598767
NP_001345456

Location (UCSC)Chr 12: 55.72 – 55.72 MbChr 10: 128.75 – 128.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000135437 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000025350 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Mertz JR, Shang E, Piantedosi R, Wei S, Wolgemuth DJ, Blaner WS (Jun 1997). "Identification and characterization of a stereospecific human enzyme that catalyzes 9-cis-retinol oxidation. A possible role in 9-cis-retinoic acid formation". J Biol Chem. 272 (18): 11744–9. doi:10.1074/jbc.272.18.11744. PMID 9115228.
  6. Simon A, Lagercrantz J, Bajalica-Lagercrantz S, Eriksson U (Feb 1997). "Primary structure of human 11-cis retinol dehydrogenase and organization and chromosomal localization of the corresponding gene". Genomics. 36 (3): 424–30. doi:10.1006/geno.1996.0487. PMID 8884265.
  7. Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (Short-Chain Dehydrogenase/Reductase and Related Enzymes) Nomenclature Initiative". Chem Biol Interact. 178 (1–3): 94–8. doi:10.1016/j.cbi.2008.10.040. PMC 2896744. PMID 19027726.
  8. "Entrez Gene: RDH5 retinol dehydrogenase 5 (11-cis/9-cis)".

Further reading


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