SCUBE1

Signal peptide, CUB domain and EGF like domain containing 1 is a protein that in humans is encoded by the SCUBE1 gene. [5]

SCUBE1
Identifiers
AliasesSCUBE1, signal peptide, CUB domain and EGF like domain containing 1
External IDsOMIM: 611746 MGI: 1890616 HomoloGene: 11224 GeneCards: SCUBE1
Orthologs
SpeciesHumanMouse
Entrez

80274

64706

Ensembl

ENSG00000159307

ENSMUSG00000016763

UniProt

Q8IWY4

Q6NZL8

RefSeq (mRNA)

NM_173050

NM_001271472
NM_001271473
NM_022723

RefSeq (protein)

NP_766638
NP_766638.2

NP_001258401
NP_001258402
NP_073560

Location (UCSC)Chr 22: 43.2 – 43.34 MbChr 15: 83.49 – 83.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology.

References

  1. GRCh38: Ensembl release 89: ENSG00000159307 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000016763 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Signal peptide, CUB domain and EGF like domain containing 1". Retrieved 2017-05-31.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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