SFRS12

Splicing factor, arginine/serine-rich 12 is a protein that in humans is encoded by the SFRS12 gene.[5][6]

SREK1
Identifiers
AliasesSREK1, SFRS12, SRrp508, SRrp86, splicing regulatory glutamic acid/lysine-rich protein 1, splicing regulatory glutamic acid and lysine rich protein 1
External IDsOMIM: 609268 MGI: 2145245 HomoloGene: 10581 GeneCards: SREK1
Orthologs
SpeciesHumanMouse
Entrez

140890

218543

Ensembl

ENSG00000153914

ENSMUSG00000032621

UniProt

Q8WXA9

Q8BZX4

RefSeq (mRNA)

NM_172592
NM_001361085

RefSeq (protein)

NP_766180
NP_001348014

Location (UCSC)Chr 5: 66.14 – 66.18 MbChr 13: 103.88 – 103.91 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002).[supplied by OMIM][6]

References

  1. GRCh38: Ensembl release 89: ENSG00000153914 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032621 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Zhang DL, Sun XJ, Ling LJ, Chen RS, Ma DL (Jun 2002). "[Molecular cloning, characterization, chromosomal assignment, genomic organization and verification of SFRS12(SRrp508), a novel member of human SR protein superfamily and a human homolog of rat SRrp86]". Yi Chuan Xue Bao. 29 (5): 377–83. PMID 12043562.
  6. "Entrez Gene: SFRS12 splicing factor, arginine/serine-rich 12".

Further reading


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