SIDT1
SID1 transmembrane family member 1 is a protein that in humans is encoded by the SIDT1 gene. [5]
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| Aliases | SIDT1, B830021E24Rik, SID-1, SID1, SID1 transmembrane family member 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 606816 MGI: 2443155 HomoloGene: 41189 GeneCards: SIDT1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
The protein encoded by this gene belongs to SID1 family of transmembrane dsRNA-gated channels. Family members transport dsRNA into cells and are required for systemic RNA interference.
References
- GRCh38: Ensembl release 89: ENSG00000072858 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000022696 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: SID1 transmembrane family member 1". Retrieved 2017-10-02.
Further reading
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
- Elhassan MO, Christie J, Duxbury MS (2012). "Homo sapiens systemic RNA interference-defective-1 transmembrane family member 1 (SIDT1) protein mediates contact-dependent small RNA transfer and microRNA-21-driven chemoresistance". J. Biol. Chem. 287 (8): 5267–77. doi:10.1074/jbc.M111.318865. PMC 3285307. PMID 22174421.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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