SMG7

Protein SMG7 is a protein that in humans is encoded by the SMG7 gene.[5][6][7][8]

SMG7
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSMG7, C1orf16, EST1C, SGA56M, nonsense mediated mRNA decay factor, SMG7 nonsense mediated mRNA decay factor
External IDsOMIM: 610964 MGI: 2682334 HomoloGene: 32235 GeneCards: SMG7
Orthologs
SpeciesHumanMouse
Entrez

9887

226517

Ensembl

ENSG00000116698

ENSMUSG00000042772

UniProt

Q92540

Q5RJH6

RefSeq (mRNA)

NM_001005507
NM_001160256
NM_001160257
NM_001359257

RefSeq (protein)

NP_001005507
NP_001153728
NP_001153729
NP_001346186

Location (UCSC)Chr 1: 183.47 – 183.6 MbChr 1: 152.71 – 152.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References

  1. GRCh38: Ensembl release 89: ENSG00000116698 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000042772 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ohnishi T, Yamashita A, Kashima I, Schell T, Anders KR, Grimson A, et al. (November 2003). "Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7". Molecular Cell. 12 (5): 1187–200. doi:10.1016/S1097-2765(03)00443-X. PMID 14636577.
  6. Fukuhara N, Ebert J, Unterholzner L, Lindner D, Izaurralde E, Conti E (February 2005). "SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway". Molecular Cell. 17 (4): 537–47. doi:10.1016/j.molcel.2005.01.010. PMID 15721257.
  7. "Entrez Gene: SMG7 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)".
  8. Yang L, Kraft VA, Pfeiffer S, Merl-Pham J, Bao X, An Y, et al. (June 2020). "Nonsense-mediated decay factor SMG7 sensitizes cells to TNFα-induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1". Molecular Oncology. 14 (10): 2420–2435. doi:10.1002/1878-0261.12754. PMC 7530794. PMID 32602581.

Further reading


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