SPRED2

Sprouty-related, EVH1 domain-containing protein 2 is a protein that in humans is encoded by the SPRED2 gene.[5]

SPRED2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSPRED2, Spred-2, sprouty related EVH1 domain containing 2, NS14
External IDsOMIM: 609292 MGI: 2150019 HomoloGene: 24918 GeneCards: SPRED2
Orthologs
SpeciesHumanMouse
Entrez

200734

114716

Ensembl

ENSG00000198369

ENSMUSG00000045671

UniProt

Q7Z698

Q924S7

RefSeq (mRNA)

NM_001128210
NM_181784

NM_033523

RefSeq (protein)

NP_001121682
NP_861449

NP_277058

Location (UCSC)Chr 2: 65.31 – 65.43 MbChr 11: 19.87 – 19.97 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

SPRED2 is a member of the Sprouty (see SPRY1)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1[5]).

References

  1. GRCh38: Ensembl release 89: ENSG00000198369 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000045671 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: SPRED2 sprouty-related, EVH1 domain containing 2".

Further reading


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