SULT1E1

Estrogen sulfotransferase is an enzyme that in humans is encoded by the SULT1E1 gene.[5][6]

SULT1E1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSULT1E1, EST, EST-1, ST1E1, STE, sulfotransferase family 1E member 1
External IDsOMIM: 600043 MGI: 98431 HomoloGene: 101388 GeneCards: SULT1E1
Orthologs
SpeciesHumanMouse
Entrez

6783

20860

Ensembl

ENSG00000109193

ENSMUSG00000029272

UniProt

P49888

P49891
Q9D566

RefSeq (mRNA)

NM_005420

NM_023135

RefSeq (protein)

NP_005411

NP_075624

Location (UCSC)Chr 4: 69.84 – 69.86 MbChr 5: 87.72 – 87.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.[6]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000109193 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000029272 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Bernier F, Leblanc G, Labrie F, Luu-The V (Dec 1994). "Structure of human estrogen and aryl sulfotransferase gene. Two mRNA species issued from a single gene". J Biol Chem. 269 (45): 28200–5. doi:10.1016/S0021-9258(18)46914-1. PMID 7961757.
  6. "Entrez Gene: SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1".

Further reading

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