Sch 642305

Sch 642305 is a chemical compound isolated from Penicillium verrucosum that inhibits bacterial DNA primase.[1]

Sch 642305
Names
Preferred IUPAC name
(4S,8aR,12S,12aR)-12-Hydroxy-4-methyl-4,5,6,7,8,8a,12,12a-octahydro-2H-3-benzoxecine-2,9(1H)-dione
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
  • InChI=1S/C14H20O4/c1-9-4-2-3-5-10-11(8-14(17)18-9)13(16)7-6-12(10)15/h6-7,9-11,13,16H,2-5,8H2,1H3/t9-,10+,11+,13-/m0/s1
    Key: WTQWDNIIFGEBSZ-WGBDABJCSA-N)O
  • C[C@H]1CCCC[C@@H]2[C@@H](CC(=O)O1)[C@H](C=CC2=O)O
Properties
C14H20O4
Molar mass 252.310 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Chu, Min; Mierzwa, Ronald; Xu, Ling; He, Ling; Terracciano, Joseph; Patel, Mahesh; Gullo, Vincent; Black, Todd; Zhao, Wenjun; Chan, Tze-Ming; McPhail, Andrew T (2003). "Isolation and Structure Elucidation of Sch 642305, a Novel Bacterial DNA Primase Inhibitor Produced by Penicilliumverrucosum". Journal of Natural Products. 66 (12): 1527–30. doi:10.1021/np0302302. PMID 14695789.


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