Deoxyschizandrin

Deoxyschizandrin is a bio-active isolate of Schisandra chinensis.[1]

Deoxyschizandrin
Names
Preferred IUPAC name
(6R,7S)-1,2,3,10,11,12-Hexamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulene
Other names
Schizandrin A; Schisandrin A; Dimethylgomisin J
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
KEGG
UNII
  • InChI=1S/C24H32O6/c1-13-9-15-11-17(25-3)21(27-5)23(29-7)19(15)20-16(10-14(13)2)12-18(26-4)22(28-6)24(20)30-8/h11-14H,9-10H2,1-8H3/t13-,14+
    Key: JEJFTTRHGBKKEI-OKILXGFUSA-N
  • C[C@@H]1CC2=CC(=C(C(=C2C3=C(C(=C(C=C3C[C@@H]1C)OC)OC)OC)OC)OC)OC
Properties
C24H32O6
Molar mass 416.514 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Deoxyschizandrin has been found to act as an agonist of the adiponectin receptor 2 (AdipoR2).[2]

References
  1. Chang, R; Li, Y; Yang, X; Yue, Y; Dou, L; Wang, Y; Zhang, W; Li, X (2013). Ma, Xin-Liang (ed.). "Protective role of deoxyschizandrin and schisantherin a against myocardial ischemia-reperfusion injury in rats". PLOS ONE. 8 (4): e61590. Bibcode:2013PLoSO...861590C. doi:10.1371/journal.pone.0061590. PMC 3631228. PMID 23620773.
  2. Sun Y, Zang Z, Zhong L, Wu M, Su Q, Gao X, Zan W, Lin D, Zhao Y, Zhang Z (2013). "Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay". PLOS ONE. 8 (5): e63354. Bibcode:2013PLoSO...863354S. doi:10.1371/journal.pone.0063354. PMC 3653934. PMID 23691032.


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