Scoparone

Scoparone is a natural organic compound with the molecular formula C11H10O4. It is found in the Chinese herb Artemisia scoparia and has been studied for its potential pharmacological properties including immunosuppression and vasorelaxation.[2][3]

Scoparone
Names
Preferred IUPAC name
6,7-Dimethoxy-2H-1-benzopyran-2-one
Other names
6,7-Dimethoxycoumarin; 6,7-Dimethylesculetin; Esculetin dimethyl ether; Scoparon; Escoparone
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.003.972
UNII
  • InChI=1S/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3
    Key: GUAFOGOEJLSQBT-UHFFFAOYSA-N
  • InChI=1/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3
    Key: GUAFOGOEJLSQBT-UHFFFAOYAO
  • O=C/2Oc1cc(OC)c(OC)cc1\C=C\2
Properties
C11H10O4
Molar mass 206.197 g·mol−1
Melting point 143 to 145 °C (289 to 293 °F; 416 to 418 K)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. "6,7-Dimethoxycoumarin". Sigma-Aldrich.
  2. Huei-Chen, Huang; Shu-Hsun, Chu; Pei-Dawn Lee Chao, PD (1991). "Vasorelaxants from Chinese herbs, emodin and scoparone, possess immunosuppressive properties". European Journal of Pharmacology. 198 (2–3): 211–3. doi:10.1016/0014-2999(91)90624-Y. PMID 1830846.
  3. Huang, Huei-Chen; Lee, Chai-Rong; Weng, Yu-I; Lee, Ming-Chih; Lee, Yuan-Teh (1992). "Vasodilator effect of scoparone (6,7-dimethoxycoumarin) from a Chinese herb". European Journal of Pharmacology. 218 (1): 123–8. doi:10.1016/0014-2999(92)90155-W. PMID 1327821.
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