Seahorse Bioscience

Seahorse Bioscience is a private company that develops and manufactures cellular bioenergetics analytical instruments. Seahorse also manufactures consumable labware products, and consumables for measuring cell metabolism.[1][2][3] The company was formerly known as Thermogenic Imaging.[4] Recognized for developing novel, leading-edge cellular bioenergetic technologies, the company is best known for developing the XF Extracellular Flux Analyzer.[5][6]

Seahorse Bioscience
TypePrivate
IndustryBioscience
Founded2001
HeadquartersNorth Billerica, Massachusetts
Key people
Jay Teich
Websitehttp://www.seahorsebio.com/

XF technology makes cellular bioenergetic studies simple, efficient and user-friendly by combining an electro-optical instrument with ‘smart plastic’ cartridges that enable the real-time measurement of cellular bioenergetics in a non-invasive, multi-well microplate format.

The first in vitro metabolic measurement, XF technology non-invasively profiles the metabolic activity of cells in minutes, offering scientists a physiologic cell-based assay for the determination of basal oxygen consumption, glycolysis rates, ATP production, and respiratory capacity in a single experiment to assess mitochondrial dysfunction.

Company President and CEO, Jay Teich founded the company in 2001 along with Andy Neilson and Jim Orrell.[1][2][7][8] Seahorse Bioscience is headquartered in North Billerica, Massachusetts, with its manufacturing facility in Chicopee, Massachusetts, and international offices in Shanghai, China and Copenhagen, Denmark.[2][3][7][8][9] In early 2016, Seahorse Bioscience was acquired by Agilent Technologies.[10]

History

Seahorse Bioscience introduced extracellular flux technology to the life sciences market in 2006.[5] XF instruments measure cellular bioenergies in real time, in a microplate, and are used for scientific research, as well as drug discovery and development.[5]

Seahorse Bioscience bought BioProcessors Corp in 2009.[11] BioProcessors Corp manufactured systems for optimizing drug manufacturing.[11]

XF Analyzers are capable of measuring the two major energy producing pathways of the cell simultaneously, mitochondrial respiration and glycolysis, allowing scientists to get the most physiologically relevant bioenergetic assay available, resulting in a better overall view of metabolism. XF technology also measures fatty acid oxidation, and metabolism of glucose and amino acids for kinetic metabolic information. Research on obesity, diabetes, cancer, and neurodegenerative diseases use this technology.[1][12]

Seahorse Bioscience raised $9.4 million to use for research and development, and company growth in 2012.[1][3] The European Union awarded the company a $3 million grant in 2012 for implementing programs to train young researchers.[13]

The company had 150 employees in May 2012.[1]

Prior investors in Seahorse Bioscience include HML Venture Partners, Commonwealth Capital Ventures, FLIR Systems Inc., New Science Ventures, and Healthcare Ventures.[1]

Products

Seahorse Bioscience sells instruments and consumables.[9] The XF Extracellular Flux Analyzer is the best-selling instrument. Consumables include Flux Paks, Microplates, and Stress Kits.[9] The Flux Analyzer can measure extracellular acidification rate (ECAR) and oxygen consumption of tissue samples. Aliquoting different cell metabolism inhibitors can also measure metrics such as glycolytic and aerobic capacity.[14]

The XF Palmitate-BSA FAO Reagent is a solution absorbed by cells. This product eliminates the need for radioactivity in fatty acid oxidation.[15]

Recognition

Seahorse Bioscience received The European Association for the Study of Obesity (EASO) poster award in 2008.[16]

“The Scientist” awarded Seahorse Bioscience’s XF96 Analyzer a Top Ten Innovation for 2009.[17] It also won the Best New Product award at the 2009 Molecular Medicine Conference.[18]

Inc.com ranked Seahorse Bioscience on the 2011 Inc. 5000 List, and also the 2012 Inc.5000 List.[3][19] In 2012 the company ranked #119 in all Health related companies and #47 for all companies in the Boston area.[19][20][21]

References
  1. Lori Valigra (May 22, 2012). "Seahorse Bioscience raises $9.4M". MHT. Retrieved January 18, 2013.
  2. "Company Overview of Seahorse Bioscience, Inc". Businessweek.com. January 18, 2013. Archived from the original on July 30, 2013. Retrieved January 18, 2013.
  3. Lori Valigra (May 22, 2012). "Seahorse Bioscience raises $9.4M for biotech labware". Boston Business Journal. Retrieved January 18, 2013.
  4. MarketLine (September 2011). "Seahorse Bioscience, Inc. (formerly Thermogenic Imaging) – Mergers & Acquisitions (M&A), Partnerships & Alliances and Investment Report". ReportLinker. Retrieved January 18, 2013.
  5. "Seahorse Bioscience Inc". BusherBiotec. Retrieved January 18, 2013.
  6. "Seahorse Bioscience Achieves Milestone in Instrument Shipments". MeshPress. October 10, 2012. Retrieved January 18, 2013.
  7. LexisNexis (November 23, 2012). "Snapshot: Seahorse Bioscience Inc". LexisNexis. {{cite web}}: Missing or empty |url= (help)
  8. "Seahorse Bioscience, Inc". InsideView. Retrieved January 18, 2013.
  9. "Seahorse Bioscience". Seahorse Bioscience. Retrieved January 18, 2013.
  10. "Agilent". Archived from the original on December 20, 2016. Retrieved June 17, 2023.
  11. Mergerstat M&A Database (November 23, 2012). "Target: BioProcessors Corp. Buyer: Seahorse Bioscience, Inc". FactSet Mergerstat, LLC. {{cite web}}: Missing or empty |url= (help)
  12. Howard Lovy (February 23, 2010). "Seahorse Bioscience Bags $5M". Xconomy. Retrieved January 18, 2013.
  13. Don Seiffert (June 1, 2012). "Seahorse Bioscience to share $3M, 3-year grant". BusinessJournal. Retrieved January 18, 2013.
  14. "Glycolysis Stress Test kit, Seahorse Glycolysis Stress Test Kit | Agilent". www.agilent.com. Retrieved December 8, 2021.
  15. "Seahorse Bioscience Launches Reagent to Make Functional Fatty Acid Oxidation (FAO) Assays Easy". Seahorse Bioscience, Inc. June 26, 2012. Retrieved January 18, 2013.
  16. "Seahorse Bioscience Receives Poster Award from the European Association for the Study of Obesity". Device Space. July 18, 2008. Retrieved January 18, 2013.
  17. "Seahorse Bioscience". Device Space. Retrieved January 18, 2013.
  18. BioSpace.com (March 13, 2009). "Seahorse Bioscience XF96 Extracellular Flux Analyzer Wins Best New Product Award for DRUG DISCOVERY at 2009 Molecular Medicine Conference". Device Space. Retrieved January 18, 2013.
  19. "Inc.5000". Inc. Retrieved January 18, 2013.
  20. "Top Companies in the Boston Metro Area on the 2012 Inc. 5000". Inc. Retrieved January 18, 2013.
  21. "Top Health Companies on the 2012 Inc. 5000". Inc. Retrieved January 18, 2013.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.