Sergiy Derevyanchenko

2007

• Defeated Victor Cotiujanschi (Moldova) 28-12
• Defeated Oliver Obradovic (Austria) RSCO 2
• Defeated Alexander Rubjuk (Estonia) 23-12
• Defeated Argenis Casimiro Núñez (Dominican Republic) RSCO 3
• Lost to Matvey Korobov (Russia) AB 2

2009

• Defeated Danijel Topalovic (Bosnia) RSC 3
• Defeated Alex Theran (Colombia) 13-8
• Defeated Adem Kılıççı (Turkey) 13-6
• Lost to Vijender Singh (India) 4-12

2008 (as a middleweight)

• Defeated Wang Jianzheng (China) 15-6
• Lost to Emilio Correa (Cuba) 4-18

Derevyanchenko ended his amateur career with a record of 390–20.

Derevyanchenko turned professional in 2014, signing with promoter Lou DiBella and fighting out of New York City.[4][6] After winning his first two fights, he signed a deal with manager Al Haymon.[7] Derevyanchenko headlined his first televised card in August 2015, facing off against Elvin Ayala in an eight-round bout aired on ShoBox,[8] winning by a wide unanimous decision, improving his record to 6–0. In August 2016, he faced former world champion Sam Soliman. In the first round, Derevyanchenko landed a left-right combination to the head, causing Soliman to take a knee. Soliman was dropped a further two times in the second-round, causing the referee to wave off the fight, giving Derevyanchenko the win by technical knockout (TKO).[9]

The IBF ordered an eliminator between Derevyanchenko and Tureano Johnson, with the winner becoming the mandatory challenger to the unified middleweight champion Gennady Golovkin. The fight was originally set for April 2016, but Johnson had to pull out due to injury.[10] The fight was rescheduled for 25 August 2017, and was televised on Fox Sports 1. Derevyanchenko slowly broke down Johnson, hurting him repeatedly throughout the fight, finally dropping Johnson in the twelfth round, at which point the referee waved off the fight.[11]

27 October 2018, he fought Daniel Jacobs for the vacant IBF middleweight title at the Hulu Theater, New York. Losing by split decision, handing Derevyanchenko the first loss of his professional career.

He fought Jack Culcay on 13 April 2019 in a final eliminator for the IBF middleweight title. Winning by unanimous decision, Derevyanchenko became the mandatory challenger for unified middleweight champion Canelo Álvarez. However, after extended negotiations between Álvarez and Derevyanchenko, both parties failed to schedule a fight before the IBF's deadline, causing the IBF to strip Álvarez of their title. Álvarez's promoter, Oscar De La Hoya, expressed his displeasure with the decision to strip Álvarez of the belt, insisting Derevyanchenko had been offered an "unprecedented amount of money for a fighter of his limited stature and limited popularity".[12]

On 5 October 2019, he faced Gennady Golovkin for the vacant IBF and IBO middleweight titles at Madison Square Garden, New York City. After a tentative start to the opening round, which saw both fighters sizing each other up with probing jabs, Golovkin fired off a six punch combination ending with a right hook to Derevyanchenko's head, dropping the Ukrainian with 1 minute left in the first round. Derevyanchenko rose to his feet within seconds, showing no signs of being hurt. The knockdown appeared to spur Derevyanchenko into action as he began to answer Golovkin's punches with his own shots for the remainder of the round. In round two, Derevyanchenko began putting three and four punch combinations together behind a single and double jab, while Golovkin stuck to single punches, landing the occasional eye-catching hook. Towards the end of the round, Golovkin opened a cut above Derevyanchenko's right eye. The action replay appeared to show the cut was caused by a left hook, however, the New York State Athletic Commission deemed it to be the result of an accidental clash of heads, meaning if the fight was stopped due to the cut before the fourth round then the fight would be ruled a no contest, after the fourth, the result would be determined by the scorecards with a technical decision rather than a technical knockout win for Golovkin if the cut was deemed to be the result of a punch. After Golovkin started the opening seconds of the third round as the aggressor, Derevyanchenko quickly fired back to the body, appearing to hurt Golovkin as he backed up and kept his elbows tucked in close to his body to protect his mid-section. Derevyanchenko took advantage of Golovkin's defensive posture, landing several clean punches to the former champion's head. Towards the end of the round Golovkin had some success with a couple of sharp hooks to the head and a right uppercut. Golovkin was the aggressor for the majority of the fourth round, having partial success, with Derevyanchenko picking his moments to fire back with two and three punch combinations and continuing to work the body. In the last minute of the round, Derevyanchenko appeared to momentarily trouble Golovkin with a straight-left hand to the body. At the beginning of the fifth round, the ringside doctor gave the cut above Derevyanchenko's right-eye a close examination before the action resumed. Derevyanchenko controlled the pace of the round with a high punch-output, continuing with three and four punch combinations with lateral movement. Golovkin, meanwhile, stuck with single hooks and probing jabs, landing a solid uppercut halfway through the round. In the final 20 seconds, Derevyanchenko landed another body shot which again appeared to hurt Golovkin, who reeled backwards with his elbows down at his side, protecting his body. The sixth was an evenly fought round with both fighters landing several clean punches to the head, although Golovkin appeared to land the more significant blows which caught the attention of the crowd. Rounds seven, eight and nine saw much of the same, back and forth engagements with Golovkin seeming to land the more eye catching blows. The tenth saw Derevyanchenko apply the pressure and back Golovkin up for the first half of the round. Golovkin had success in the last minute with left and right hooks landing on Derevyanchenko's head, only to see the Ukrainian answer with his own solid shots and back Golovkin up once again in the final 30 seconds of the round. The eleventh and twelfth were closely contested, both fighters having success, with Golovkin again appearing to land the more catching punches in the twelfth and final round. After 12 hard fought rounds, Golovkin won by unanimous decision with two judges scoring the bout 115–112 and the third scoring it 114–113, all in favour of Golovkin. According to CompuBox stats, Golovkin landed a total of 243 (33.7%) punches out of 720, with 136 (43.3%) of 314 power punches, while Derevyanchenko landed a total of 230 (31.2%) punches out of 738, with 138 (29.3%) out of 472 power punches—the most an opponent has landed on Golovkin to date.[13] In a post fight interview, promoter Eddie Hearn, who lead the promotion of DAZN in the US, stated: "...he won't say it, but Gennady has been ill, basically all week",[14] alluding to the reason Golovkin did not appear on top form during the fight.

26 September 2020, he fought Jermall Charlo for the WBC middleweight title at the Mohegan Sun Arena, Uncasville. Derevyanchenko fought a tough fight, but Charlo's powerful jab and good game plan were too much for the Ukrainian. Charlo connected on more punches than Derevyanchenko, and ultimately deserved the unanimous decision win, with the scorecards reading 118–110, 117-111 and 116–112 in favor of Charlo.[15]