Shuvo Roy

Roy received most of his education in Uganda, where his father worked as a public health physician.[1]

Roy later completed his education and earned his BS degree from University of Mount Union, Ohio in 1992. He then earned his MS degree in Electrical Engineering and Applied Physics from Case Western Reserve University in 1995. He went on to earn his PhD degree from the same school in 2001.[2]

Roy has developed silicon nanopore membranes (SNM) to achieve high-efficiency blood ultrafiltration while selectively retaining specific solutes and serving as an immunoprotective barrier for encapsulated cells. The SNM are the fundamental underlying technology for the development of an implantable bioartificial kidney.[3]

Using this technology, he has shown feasibility for an implantable bioartificial pancreas (iBAP). Previous attempts to develop a bioartificial pancreas have been severely limited by insufficient mass transfer and a limited supply of beta cells, but Roy says that ultra-high hydraulic permeability characteristic of the SNM will enable appropriate mass transport (especially oxygen, glucose, and insulin) to achieve optimal beta cell performance, while the ultra-selective pore characteristic of the SNM enable unprecedented immunoisolation. Also the iBAP can utilize a human stem cell derived fully functional beta cell that provides and unlimited supply of beta cells.[4]

He is a founding member of the University of California, San Francisco Pediatric Device Consortium.[2]

• M. Mehregany and S. Roy, "Introduction to MEMS", in Microengineering for Aerospace Systems, H. Helvajian, Ed., Aerospace Press, Los Angeles, CA, USA, 1999
• S. Roy, L.A. Ferrara, A.J. Fleischman, and E.C. Benzel, "MEMS and Neurosurgery", in Encyclopedia of BioMEMS and Bionanotechnology – Volume III: BioMEMS and Biomedical Nanotechnology, T.A. Desai, S. Bhatia, and M. Ferrari, Eds., Springer, New York, NY, USA, 2006
• W.H. Fissell, S. Roy, A.J. Fleischman, and H.D. Humes, “Cell Therapy of Renal Failure”, in Cell Therapy, D. Garcia-Olmo, J.M. Garcia-Verdugo, J. Alemany, and J.A. Gutierrez-Fuentes, Eds., McGraw-Hill, Madrid, SPAIN, 2008
• A.J. Fleischman, S. Srivanas, C. Chandrana, and S. Roy, “Miniature High Frequency Focused Ultrasonic Transducers for Minimally Invasive Imaging Procedures”, in Biomedical Applications of Electroactive Polymer Actuators, F. Carpi and E. Smela, Eds., John Wiley and Sons, Chichester, West Sussex, UK, 2009[2]

• 2003 MIT TR100 Award, Top 100 Young Innovators, Technology Review Magazine[5]
• 2004 NASA Group Achievement Award, Harsh Environment MEMS
• Harry Wm. and Diana V. Hind Distinguished Professorship in Pharmaceutical Sciences II in the University of California, San Francisco School of Pharmacy.[2]
• KidneyX Redesign Dialysis prize.

• Pettypiece, Shannon (5 December 2005). "Startup senses a need for orthopedic detection device". Crain's Cleveland Business. p. 11.
• Roy, Sandip (10 December 2010). "Coming full circle". India Abroad. p. M3.

• Shuvo Roy publications indexed by Google Scholar