Solute carrier family 10 member 4

Solute carrier family 10 member 4 is a protein that in humans is encoded by the SLC10A4 gene.[5] In mice, it appears to promote acidification of synaptic vesicles containing monoamines, enhancing their uptake, and is co-expressed with VMAT2 and VAChT.[6]

SLC10A4
Identifiers
AliasesSLC10A4, P4, solute carrier family 10 member 4
External IDsMGI: 3606480 HomoloGene: 15495 GeneCards: SLC10A4
Orthologs
SpeciesHumanMouse
Entrez

201780

231290

Ensembl

ENSG00000145248

ENSMUSG00000029219

UniProt

Q96EP9

Q3UEZ8

RefSeq (mRNA)

NM_152679

NM_173403

RefSeq (protein)

NP_689892

NP_775579

Location (UCSC)Chr 4: 48.48 – 48.49 MbChr 5: 73.16 – 73.17 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000145248 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000029219 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Solute carrier family 10 member 4". Retrieved 2016-04-17.
  6. Larhammar M, Patra K, Blunder M, Emilsson L, Peuckert C, Arvidsson E, Rönnlund D, Preobraschenski J, Birgner C, Limbach C, Widengren J, Blom H, Jahn R, Wallén-Mackenzie Å, Kullander K (March 2015). "SLC10A4 is a vesicular amine-associated transporter modulating dopamine homeostasis". Biological Psychiatry. 77 (6): 526–36. doi:10.1016/j.biopsych.2014.07.017. hdl:11858/00-001M-0000-0025-7742-E. PMID 25176177. S2CID 6665524.

Further reading

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