Spontaneous absolute asymmetric synthesis

Spontaneous absolute asymmetric synthesis is a chemical phenomenon that stochastically generates chirality based on autocatalysis and small fluctuations in the ratio of enantiomers present in a racemic mixture.[1] In certain reactions which initially do not contain chiral information, stochastically distributed enantiomeric excess can be observed. The phenomenon is different from chiral amplification, where enantiomeric excess is present from the beginning and not stochastically distributed. Hence, when the experiment is repeated many times, the average enantiomeric excess approaches 0%.[2] The phenomenon has important implications concerning the origin of homochirality in nature.[3]

References
  1. Tsuneomi Kawasaki, Kenta Suzuki, Masako Shimizu, Keisuke Ishikawa and Kenso Soai, Chirality, Volume 18, Issue 7, pages 479–482, 2006, doi:10.1002/chir.20273
  2. Kenta Suzuki, Kunihiko Hatase, Daisuke Nishiyama, Tsuneomi Kawasaki, Kenso Soai, Journal of Systems Chemistry 2010, 1:5 (18 August 2010), doi:10.1186/1759-2208-1-5
  3. "Interview: In the beginning..." Highlights in Chemical Science (5). 2008. Archived from the original on March 26, 2016. Retrieved June 18, 2014.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.