TCTN3

Tectonic family member 3 is a protein in humans that is encoded by the TCTN3 gene. [5]

TCTN3
Identifiers
Aliases	TCTN3, C10orf61, JBTS18, OFD4, TECT3, tectonic family member 3
External IDs	OMIM: 613847 MGI: 1914840 HomoloGene: 9221 GeneCards: TCTN3
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q24.1 Start 95,659,823 bp[1] End 95,694,143 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 C3 Start 40,584,890 bp[2] End 40,600,677 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis stromal cell of endometrium islet of Langerhans caput epididymis right lobe of thyroid gland pancreatic ductal cell left lobe of thyroid gland gallbladder rectum parotid gland Top expressed in fourth ventricle spermatocyte saccule spermatid islet of Langerhans visual cortex otic placode seminiferous tubule medullary collecting duct superior frontal gyrus More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 26123 67590 Ensembl ENSG00000119977 ENSMUSG00000025008 UniProt Q6NUS6 Q8R2Q6 RefSeq (mRNA) NM_001143973 NM_015631 NM_026260 NM_001365072 RefSeq (protein) NP_001137445 NP_056446 NP_080536 NP_001352001 Location (UCSC) Chr 10: 95.66 – 95.69 Mb Chr 19: 40.58 – 40.6 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and development of the neural tube. Mutations in this gene have been associated with Oral-facial-digital syndrome IV and Joubert syndrome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012].