TIMM10

Mitochondrial import inner membrane translocase subunit Tim10 is an enzyme that in humans is encoded by the TIMM10 gene.[5][6]

TIMM10
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTIMM10, TIM10, TIM10A, translocase of inner mitochondrial membrane 10 homolog (yeast), translocase of inner mitochondrial membrane 10, TIMM10A
External IDsOMIM: 602251 MGI: 1353429 HomoloGene: 40845 GeneCards: TIMM10
Orthologs
SpeciesHumanMouse
Entrez

26519

30059

Ensembl

ENSG00000134809

ENSMUSG00000027076

UniProt

P62072

P62073

RefSeq (mRNA)

NM_012456

NM_013899

RefSeq (protein)

NP_036588

NP_038927

Location (UCSC)Chr 11: 57.53 – 57.53 MbChr 2: 84.66 – 84.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

TIMM10 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM][6]

References

  1. GRCh38: Ensembl release 89: ENSG00000134809 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027076 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Jin H, Kendall E, Freeman TC, Roberts RG, Vetrie DL (Feb 2000). "The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins". Genomics. 61 (3): 259–67. doi:10.1006/geno.1999.5966. PMID 10552927.
  6. "Entrez Gene: TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)".

Further reading


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