TMSB10

Thymosin beta-10 is a protein that in humans is encoded by the TMSB10 gene.[3][4][5] TMSB10 is a member of the beta-thymosin family of peptides.

TMSB10
Identifiers
AliasesTMSB10, MIG12, TB10, thymosin beta 10
External IDsOMIM: 188399 GeneCards: TMSB10
Orthologs
SpeciesHumanMouse
Entrez

9168

n/a

Ensembl

ENSG00000034510

n/a

UniProt

P63313

n/a

RefSeq (mRNA)

NM_021103

n/a

RefSeq (protein)

NP_066926

n/a

Location (UCSC)Chr 2: 84.91 – 84.91 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

TMSB10 plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).

References

  1. GRCh38: Ensembl release 89: ENSG00000034510 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. McCreary V, Kartha S, Bell GI, Toback FG (Jun 1988). "Sequence of a human kidney cDNA clone encoding thymosin beta 10". Biochem Biophys Res Commun. 152 (2): 862–6. doi:10.1016/S0006-291X(88)80118-9. PMID 3365256.
  4. Santelli G, Califano D, Chiappetta G, Vento MT, Bartoli PC, Zullo F, Trapasso F, Viglietto G, Fusco A (Oct 1999). "Thymosin beta-10 gene overexpression is a general event in human carcinogenesis". Am J Pathol. 155 (3): 799–804. doi:10.1016/s0002-9440(10)65178-4. PMC 1866886. PMID 10487837.
  5. "Entrez Gene: TMSB10 thymosin, beta 10".

Further reading


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