TNFAIP1

BTB/POZ domain-containing protein TNFAIP1 is a protein that in humans is encoded by the TNFAIP1 gene.[5][6][7]

TNFAIP1
Identifiers
AliasesTNFAIP1, B12, B61, BTBD34, EDP1, hBACURD2, TNF alpha induced protein 1
External IDsOMIM: 191161 MGI: 104961 HomoloGene: 22519 GeneCards: TNFAIP1
Orthologs
SpeciesHumanMouse
Entrez

7126

21927

Ensembl

ENSG00000109079

ENSMUSG00000017615

UniProt

Q13829

O70479

RefSeq (mRNA)

NM_021137

NM_001159392
NM_009395

RefSeq (protein)

NP_066960

NP_001152864
NP_033421

Location (UCSC)Chr 17: 28.34 – 28.35 MbChr 11: 78.41 – 78.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000109079 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000017615 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Dixit VM, Green S, Sarma V, Holzman LB, Wolf FW, O'Rourke K, Ward PA, Prochownik EV, Marks RM (Mar 1990). "Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin". J Biol Chem. 265 (5): 2973–8. doi:10.1016/S0021-9258(19)39896-5. PMID 2406243.
  6. Holzman LB, Marks RM, Dixit VM (Dec 1990). "A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein". Mol Cell Biol. 10 (11): 5830–8. doi:10.1128/MCB.10.11.5830. PMC 361366. PMID 2233719.
  7. "Entrez Gene: TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)".

Further reading


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