TTBK1
Tau tubulin kinase 1 is a protein that in humans is encoded by the TTBK1 gene.[5]
References
- GRCh38: Ensembl release 89: ENSG00000146216 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000015599 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Tau tubulin kinase 1". Retrieved 2017-03-23.
Further reading
- Sato S, Xu J, Okuyama S, Martinez LB, Walsh SM, Jacobsen MT, Swan RJ, Schlautman JD, Ciborowski P, Ikezu T (2008). "Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1". J. Neurosci. 28 (53): 14511–21. doi:10.1523/JNEUROSCI.3417-08.2008. PMC 6671237. PMID 19118186.
- Vázquez-Higuera JL, Martínez-García A, Sánchez-Juan P, Rodríguez-Rodríguez E, Mateo I, Pozueta A, Frank A, Valdivieso F, Berciano J, Bullido MJ, Combarros O (2011). "Genetic variations in tau-tubulin kinase-1 are linked to Alzheimer's disease in a Spanish case-control cohort". Neurobiol. Aging. 32 (3): 550.e5–9. doi:10.1016/j.neurobiolaging.2009.12.021. PMID 20096481. S2CID 5587797.
- Vázquez-Higuera JL, Martínez-García A, Sánchez-Juan P, Rodríguez-Rodríguez E, Mateo I, Pozueta A, Frank A, Valdivieso F, Berciano J, Bullido MJ, Combarros O (2011). "Genetic variations in tau-tubulin kinase-1 are linked to Alzheimer's disease in a Spanish case-control cohort". Neurobiol. Aging. 32 (3): 550.e5–9. doi:10.1016/j.neurobiolaging.2009.12.021. PMID 20096481. S2CID 5587797.
- Yu NN, Yu JT, Xiao JT, Zhang HW, Lu RC, Jiang H, Xing ZH, Tan L (2011). "Tau-tubulin kinase-1 gene variants are associated with Alzheimer's disease in Han Chinese". Neurosci. Lett. 491 (1): 83–6. doi:10.1016/j.neulet.2011.01.011. PMID 21219968. S2CID 6421145.
- Lund H, Cowburn RF, Gustafsson E, Strömberg K, Svensson A, Dahllund L, Malinowsky D, Sunnemark D (2013). "Tau-tubulin kinase 1 expression, phosphorylation and co-localization with phospho-Ser422 tau in the Alzheimer's disease brain". Brain Pathol. 23 (4): 378–89. doi:10.1111/bpa.12001. PMC 8029021. PMID 23088643. S2CID 30089308.
- Kiefer SE, Chang CJ, Kimura SR, Gao M, Xie D, Zhang Y, Zhang G, Gill MB, Mastalerz H, Thompson LA, Cacace AM, Sheriff S (2014). "The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor". Acta Crystallogr F. 70 (Pt 2): 173–81. doi:10.1107/S2053230X14000144. PMC 3936456. PMID 24637750.
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