Ternatin heptapeptide

Ternatin is a mushroom heptapeptide that suppresses hyperglycemia in vivo.[2]

Ternatin heptapeptide
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C37H67N7O8/c1-16-22(8)28-37(52)43(14)25(11)35(50)44(15)27(18-20(4)5)32(47)38-26(17-19(2)3)36(51)42(13)24(10)34(49)41(12)23(9)31(46)40-29(33(48)39-28)30(45)21(6)7/h19-30,45H,16-18H2,1-15H3,(H,38,47)(H,39,48)(H,40,46)
    Key: ZMFVAIFXJWEOMH-UHFFFAOYSA-N
  • (natural): InChI=1S/C37H67N7O8/c1-16-22(8)28-37(52)43(14)25(11)35(50)44(15)27(18-20(4)5)32(47)38-26(17-19(2)3)36(51)42(13)24(10)34(49)41(12)23(9)31(46)40-29(33(48)39-28)30(45)21(6)7/h19-30,45H,16-18H2,1-15H3,(H,38,47)(H,39,48)(H,40,46)/t22-,23+,24-,25-,26-,27-,28+,29+,30+/m0/s1
    Key: ZMFVAIFXJWEOMH-PTPSPKLBSA-N
  • CCC(C)C1C(=O)N(C(C(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)NC(C(=O)N1)C(C(C)C)O)C)C)C)C)CC(C)C)CC(C)C)C)C)C
  • (natural): CC[C@H](C)[C@H]1NC(=O)[C@@H]([C@H](O)C(C)C)NC(=O)[C@@H](C)N(C)C(=O)[C@H](C)N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C)N(C)C1=O
Properties
C37H67N7O8
Molar mass 737.984 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. "Human Metabolome Database: Showing metabocard for Ternatin (HMDB0040991)". hmdb.ca.
  2. Kobayashi, M.; Kawashima, H.; Takemori, K.; Ito, H.; Murai, A.; Masuda, S.; Yamada, K.; Uemura, D.; Horio, F. (2012). "Ternatin, a cyclic peptide isolated from mushroom, and its derivative suppress hyperglycemia and hepatic fatty acid synthesis in spontaneously diabetic KK-A(y) mice". Biochemical and Biophysical Research Communications. 427 (2): 299–304. doi:10.1016/j.bbrc.2012.09.045. PMID 23000156.
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