Translocated actin-recruiting phosphoprotein

The translocated actin-recruiting phosphoprotein (Tarp) is a protein that may mediate the invasion of epithelial cells by Chlamydia trachomatis using a type three secretion system.[1][2][3][4][5]

Translocated actin-recruiting phosphoprotein
Identifiers
Symboltarp
UniProtO84462
Search for
StructuresSwiss-model
DomainsInterPro

References
  1. Wang J, Chen L, Chen F, Zhang X, Zhang Y, Baseman J, Perdue S, Yeh IT, Shain R, Holland M, Bailey R, Mabey D, Yu P, Zhong G (2009), "A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice", Vaccine, 27 (22): 2967–2980, doi:10.1016/j.vaccine.2009.02.095, PMC 2680781, PMID 19428908
  2. Clifton DR, Dooley CA, Grieshaber SS, Carabeo RA, Fields KA, Hackstadt T (2005), "Tyrosine phosphorylation of the Chlamydial effector protein Tarp is species specific and not required for recruitment of actin", Infection and Immunity, 73 (7): 3860–3868, doi:10.1128/IAI.73.7.3860-3868.2005, PMC 1168552, PMID 15972471
  3. Clifton DR, Fields KA, Grieshaber SS, Dooley CA, Fischer ER, Mead DJ, Carabeo RA, Hackstadt T (2004), "A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin", Proceedings of the National Academy of Sciences of the USA, 101 (27): 10166–10171, doi:10.1073/pnas.0402829101, PMC 454183, PMID 15199184
  4. Engel J (2004), "Tarp and Arp: How Chlamydia induces its own entry", Proceedings of the National Academy of Sciences of the USA, 101 (27): 9947–9948, Bibcode:2004PNAS..101.9947E, doi:10.1073/pnas.0403633101, PMC 454194, PMID 15226494
  5. "Translocated actin-recruiting phosphoprotein [Chlamydia trachomatis] - Protein - NCBI".


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