Tripartite motif containing 34

Tripartite motif containing 34 is a protein that, in humans, is encoded by the TRIM34 gene.[3]

TRIM34
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesTRIM34, IFP1, RNF21, tripartite motif containing 34
External IDsOMIM: 605684 HomoloGene: 136478 GeneCards: TRIM34
Orthologs
SpeciesHumanMouse
Entrez

53840

n/a

Ensembl

ENSG00000258659

n/a

UniProt

Q9BYJ4

n/a

RefSeq (mRNA)

NM_130390
NM_001003827
NM_021616
NM_130389

n/a

RefSeq (protein)

NP_001003827
NP_067629
NP_569074

n/a

Location (UCSC)Chr 11: 5.62 – 5.64 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Function

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members.

References
  1. GRCh38: Ensembl release 89: ENSG00000258659 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: Tripartite motif containing 34". Retrieved 2016-09-01.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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