UIC
Education
- University of Illinois Chicago, a public four-year university in Chicago, Illinois, United States
- UIC Flames, the intercollegiate athletic program of the University of Illinois Chicago
- Underwood International College, an affiliated department of Yonsei University, Seoul, South Korea
- United International College, a public liberal arts college in Zhuhai, Guangdong, China
Government
- Uganda Insurance Commission, a government agency
- Unit Identification Code, an alphanumeric code used by the United States Department of Defense
- Underground Injection Control Program, a U.S. environmental regulatory program
Organisations
- International Union of Railways (Union Internationale des Chemins de fer), an international rail transport industry body
- UEFA Intertoto Cup, an association football tournament for member clubs of UEFA
- Union of Islamic Courts, an armed group in Somalia, now called the "Supreme Islamic Courts Council"
- United Industrial Corporation Ltd, a Singapore real estate holding company owned by JG Summit Holdings
- Uttarakhand Information Commission, a state government organisation of Uttarakhand, India
Computing
- Uranium Information Centre, a defunct website sponsored by uranium mining companies
- User identification code, the user number of the Files-11 file system in the RSX-11 operating system
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