U.S. Route 15 in North Carolina

US 15/US 501 turns left in Durham

From the South Carolina state line, US 15 is in concurrency with US 401 to Laurinburg. Merging with US 501, it becomes what is known as "15-501" ("Fifteen Five-o-one"), a concurrency that extends for 106 miles (171 km) across central North Carolina; US 15 also the dominant partner, using its milemarkers along the route. After Laurinburg, it goes north to Aberdeen, linking briefly with US 1 before continuing to Pinehurst. In Pinehurst, US 15/US 501 goes through a rare roundabout, then continues north, through Carthage, back to US 1. After another brief concurrency with US 1 through Sanford, it exits off the freeway and goes due north to Pittsboro. After Pittsboro, US 15/US 501 becomes an expressway, connecting the cities of Chapel Hill and Durham; this section of the route is famous because of the two universities it connects: University of North Carolina at Chapel Hill and Duke University. Though the road is a symbol of the separation of the Carolina–Duke rivalry, the North Carolina Department of Transportation has been trying to remedy that by making the route a superstreet for better traffic flow.[3] In Durham, US 15/US 501 upgrades to an urban freeway, allowing for quick access from south Durham to north; the freeway ends merging into Interstate 85 (I-85). At exit 176B (on I-85), US 501 splits off toward Roxboro, while US 15 continues with I-85 toward Oxford.

After Durham, US 15 continues to follow I-85 till exit 186A, where it goes first to Creedmoor, then on into Oxford. After going through downtown Oxford, it continues north, near Mayo Lake, to Clarksville, Virginia.

Established in 1927, it was aligned along North Carolina Highway 75 from the South Carolina state line, through Rockingham, Pinehurst, and Durham, to the Virginia state line.[4]

• Special routes of U.S. Route 15

• Media related to U.S. Route 15 in North Carolina at Wikimedia Commons
• NCRoads.com: U.S. 15