VAMP5
Vesicle-associated membrane protein 5 (VAMP-5) is a synaptobrevin protein encoded in the human by the VAMP5 gene.[1][2]
| vesicle-associated membrane protein 5 (myobrevin) | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | VAMP5 | ||||||
| NCBI gene | 10791 | ||||||
| HGNC | 12646 | ||||||
| OMIM | 607029 | ||||||
| RefSeq | NM_006634 | ||||||
| UniProt | O95183 | ||||||
| Other data | |||||||
| Locus | Chr. 2 p11.2 | ||||||
| |||||||
Function
VAMPs (synaptobrevins) along with syntaxins and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis.[2]
References
- Zeng Q, Subramaniam VN, Wong SH, Tang BL, Parton RG, Rea S, James DE, Hong W (September 1998). "A novel synaptobrevin/VAMP homologous protein (VAMP5) is increased during in vitro myogenesis and present in the plasma membrane". Molecular Biology of the Cell. 9 (9): 2423–37. doi:10.1091/mbc.9.9.2423. PMC 25509. PMID 9725904.
- "Entrez Gene: STX12 syntaxin 12".
External links
- VAMP5 protein, human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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