VANGL2

VANGL planar cell polarity protein 2 is a protein that in humans is encoded by the VANGL2 gene. [5]

VANGL2
Identifiers
AliasesVANGL2, LPP1, LTAP, STB1, STBM, STBM1, VANGL planar cell polarity protein 2
External IDsOMIM: 600533 MGI: 2135272 HomoloGene: 62161 GeneCards: VANGL2
Orthologs
SpeciesHumanMouse
Entrez

57216

93840

Ensembl

ENSG00000162738

ENSMUSG00000026556

UniProt

Q9ULK5

Q91ZD4

RefSeq (mRNA)

NM_020335

NM_033509

RefSeq (protein)

NP_065068

NP_277044

Location (UCSC)Chr 1: 160.4 – 160.43 MbChr 1: 171.83 – 171.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

The protein encoded by the VANGL2 gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. [provided by RefSeq, Sep 2011].

References

  1. GRCh38: Ensembl release 89: ENSG00000162738 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000026556 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: VANGL planar cell polarity protein 2". Retrieved 2018-07-05.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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