Veratric acid

Veratric acid, also known as 3,4-dimethoxybenzoic acid, is a benzoic acid. It is a plant metabolite found in species such as Hypericum laricifolium, Artemisia sacrorum, and Zeyheria montana.[1][2]

Veratric acid
Names
IUPAC name
3,4-Dimethoxybenzoic acid
Other names
Dimethylprotocatechuic acid
Identifiers
3D model (JSmol)
ECHA InfoCard 100.002.015
  • COC1=C(C=C(C=C1)C(=O)O)OC
Properties
C9H10O4
Molar mass 182.175 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Uses

Medical research

A 2023 study at SRM Institute of Science and Technology suggests that veratric acid has apoptotic and antiproliferative effects against triple negative breast cancer cells. These effects were substantially increased when polydopamine nanoparticles were used as a sustained release drug carrier. [3]

References
  1. da Silveira, José Chagas; Gottlieb, Otto R.; de Oliveira, Geovane G. (1975-08-01). "Zeyherol, a dilignol from Zeyhera digitalis". Phytochemistry. 14 (8): 1829–1830. doi:10.1016/0031-9422(75)85304-0. ISSN 0031-9422.
  2. PubChem. "3,4-Dimethoxybenzoic acid". pubchem.ncbi.nlm.nih.gov. Retrieved 2023-04-16.
  3. Harini, Ganesh; Ganesh, S. Shree; Anushikaa, Ramprasad; Bharathi, Ramanathan; Aravind, Sankaranarayanan; Vatsala, Kumari; Shanmugavadivu, Abinaya; Selvamurugan, Nagarajan (2023-05-04). "Antiproliferative and Apoptotic Effects of pH-responsive Veratric acid-loaded Polydopamine Nanoparticles in Human Triple Negative Breast Cancer Cells". Chemistry & Biodiversity: e202201006. doi:10.1002/cbdv.202201006. ISSN 1612-1880. PMID 37140976.


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