Verrulactone

Verrulactones are alternariol-derived antimicrobial chemical compounds isolated from Penicillium.[1]

Verrulactone

Chemical structure of verrulactone A
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • A: InChI=1S/C28H18O12/c1-37-9-3-11-19(13(29)5-9)27(35)39-17-7-15(31)25(33)23(21(11)17)24-22-12-4-10(38-2)6-14(30)20(12)28(36)40-18(22)8-16(32)26(24)34/h3-8,29-34H,1-2H3
    Key: ZSHZQCWUSDSOFB-UHFFFAOYSA-N
  • B: InChI=1S/C28H18O12/c1-37-9-3-11-12-7-16(31)25(34)23(26(12)40-28(36)19(11)14(29)5-9)22-21-13-4-10(38-2)6-15(30)20(13)27(35)39-18(21)8-17(32)24(22)33/h3-8,29-34H,1-2H3
    Key: KILSNFDREQHTBU-UHFFFAOYSA-N
  • A: COC1=CC2=C(C(=C1)O)C(=O)OC3=C2C(=C(C(=C3)O)O)C4=C(C(=CC5=C4C6=C(C(=CC(=C6)OC)O)C(=O)O5)O)O
  • B: COC1=CC2=C(C(=C1)O)C(=O)OC3=C(C(=C(C=C23)O)O)C4=C(C(=CC5=C4C6=C(C(=CC(=C6)OC)O)C(=O)O5)O)O
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Kim, N.; Sohn, M. J.; Kim, C. J.; Kwon, H. J.; Kim, W. G. (2012). "Verrulactones a and B, new inhibitors of Staphylococcus aureus enoyl-ACP reductase produced by Penicillium verruculosum F375". Bioorganic & Medicinal Chemistry Letters. 22 (7): 2503–6. doi:10.1016/j.bmcl.2012.02.001. PMID 22377515.
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