WDR6

WD repeat-containing protein 6 is a protein that in humans is encoded by the WDR6 gene.[5]

WDR6
Identifiers
AliasesWDR6, WD repeat domain 6, Trm734
External IDsOMIM: 606031 MGI: 1930140 HomoloGene: 117682 GeneCards: WDR6
Orthologs
SpeciesHumanMouse
Entrez

11180

83669

Ensembl

ENSG00000178252

ENSMUSG00000066357

UniProt

Q9NNW5

Q99ME2

RefSeq (mRNA)

NM_018031
NM_001320546
NM_001320547

NM_031392

RefSeq (protein)

NP_001307475
NP_001307476
NP_060501

NP_113569

Location (UCSC)Chr 3: 49.01 – 49.02 MbChr 9: 108.45 – 108.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is ubiquitously expressed in adult and fetal tissues.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000178252 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000066357 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: WDR6 WD repeat domain 6".

Further reading


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