Wohl–Aue reaction

The Wohl–Aue reaction is an organic reaction between an aromatic nitro compound and an aniline to form a phenazine in presence of an alkali base.[1][2] An example is the reaction between nitrobenzene and aniline:

The Wohl-Aue reaction
The Wohl-Aue reaction

The reaction is named after Alfred Wohl and W. Aue.

References

  1. Alfred Wohl and W. Aue (1901). "Über die Einwirkung von Nitrobenzol auf Anilin bei Gegenwart von Alkali". Chemische Berichte. 34 (2): 2442–2450. doi:10.1002/cber.190103402183. hdl:2027/uc1.b2652529.
  2. Irwin J. Pachter and Milton C. Kloetzel (1951). "The Wohl-Aue Reaction. I. Structure of Benzo [a] phenazine Oxides and Syntheses of 1,6-Dimethoxyphenazine and 1,6-Dichlorophenazine". J. Am. Chem. Soc. 73 (10): 4958–4961. doi:10.1021/ja01154a144.
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