Xenotropic and polytropic retrovirus receptor 1

XPR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5IJH
Identifiers
Aliases	XPR1, SYG1, X3, IBGC6, xenotropic and polytropic retrovirus receptor 1, SLC53A1
External IDs	OMIM: 605237 MGI: 97932 HomoloGene: 134226 GeneCards: XPR1
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	180,890,279 bp[1]
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)[2]
End	155,293,161 bp[2]
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; secondary oocyte; ; endothelial cell; ; pancreatic epithelial cell; ; islet of Langerhans; ; Brodmann area 23; ; right ventricle; ; endometrium; ; middle temporal gyrus; ; bronchial epithelial cell;
	Top expressed in
	median eminence; ; ventromedial nucleus; ; arcuate nucleus; ; habenula; ; ascending aorta; ; dorsomedial hypothalamic nucleus; ; extensor digitorum longus muscle; ; mammillary body; ; triceps brachii muscle; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; transmembrane signaling receptor activity; phosphate ion transmembrane transporter activity; inositol hexakisphosphate binding; virus receptor activity; efflux transmembrane transporter activity; signaling receptor activity;
Cellular component	integral component of membrane; membrane; intrinsic component of plasma membrane; plasma membrane; cytoplasm; Golgi apparatus;
Biological process	viral entry into host cell; G protein-coupled receptor signaling pathway; response to virus; cellular phosphate ion homeostasis; phosphate ion transmembrane transport; phosphate ion transport; cellular response to phosphate starvation;
	Sources:Amigo / QuickGO
Orthologs
	9213
	19775
	ENSG00000143324
	ENSMUSG00000026469
	Q9UBH6
	Q9Z0U0
	NM_004736; NM_001135669; NM_001328662
	NM_011273
	NP_001129141; NP_001315591; NP_004727
	NP_035403
	Wikidata
View/Edit Human	View/Edit Mouse

Xenotropic and polytropic retrovirus receptor 1 is a protein that in humans is encoded by the XPR1 gene. [5]

References

GRCh38: Ensembl release 89: ENSG00000143324 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000026469 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Xenotropic and polytropic retrovirus receptor 1". Retrieved 2017-03-31.

Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
Bhosle S, Suppiah S, Molinaro R, Liang Y, Arnold R, Diehl W, Makarova N, Blackwell J, Petros J, Liotta D, Hunter E, Ly H (2010). "Evaluation of cellular determinants required for in vitro xenotropic murine leukemia virus-related virus entry into human prostate cancer and noncancerous cells". J. Virol. 84 (13): 6288–96. doi:10.1128/JVI.00274-10. PMC 2903252. PMID 20410264.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143324 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026469 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Xenotropic and polytropic retrovirus receptor 1". Retrieved 2017-03-31.

Xenotropic and polytropic retrovirus receptor 1

References

Further reading