YY1AP1

YY1AP1
Identifiers
Aliases	YY1AP1, HCCA1, HCCA2, YAP, YY1AP, YY1 associated protein 1, GRNG
External IDs	OMIM: 607860 HomoloGene: 130398 GeneCards: YY1AP1
Gene location (Human)
Chr.	Chromosome 1 (human)[1]
End	155,689,000 bp[1]
RNA expression pattern
	Top expressed in
	Achilles tendon; ; oocyte; ; secondary oocyte; ; blood; ; corpus callosum; ; gastrocnemius muscle; ; saphenous vein; ; nipple; ; cancellous bone; ; superficial temporal artery;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; nucleus; fibrillar center; Ino80 complex; nucleoplasm; nucleolus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; cell differentiation; regulation of cell cycle; cell population proliferation;
	Sources:Amigo / QuickGO
Orthologs
	55249
	n/a
	ENSG00000163374
	n/a
	Q9H869
	n/a
NM_001198899; NM_001198900; NM_001198901; NM_001198902; NM_001198903;
	NM_001198904; NM_001198905; NM_001198906; NM_018253; NM_139118; NM_139119; NM_139120; NM_139121
	n/a
NP_001185828; NP_001185829; NP_001185830; NP_001185831; NP_001185832;
	NP_001185833; NP_001185834; NP_001185835; NP_060723; NP_620829; NP_620830; NP_620832
	n/a
	Wikidata
View/Edit Human

YY1-associated protein 1 is a protein that in humans is encoded by the YY1AP1 gene.[3][4]

The encoded gene product presumably interacts with YY1 protein; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms.[4]

References

GRCh38: Ensembl release 89: ENSG00000163374 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Wang ZX, Wang HY, Wu MC (Nov 2001). "Identification and characterization of a novel human hepatocellular carcinoma-associated gene". Br J Cancer. 85 (8): 1162–7. doi:10.1054/bjoc.2001.2059. PMC 2375167. PMID 11710830.
"Entrez Gene: YY1AP1 YY1 associated protein 1".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Wang Z, Hu G, Wang H, Wu M (2002). "[Clone of a novel liver cancer associated gene and analysis of the secondary structures of the predicted protein]". Zhonghua Gan Zang Bing Za Zhi. 10 (1): 25–7. PMID 11856496.
Zeng JZ, Wang HY, Chen ZJ, et al. (2002). "Molecular cloning and characterization of a novel gene which is highly expressed in hepatocellular carcinoma". Oncogene. 21 (32): 4932–43. doi:10.1038/sj.onc.1205652. PMID 12118372.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Wang CY, Liang YJ, Lin YS, et al. (2004). "YY1AP, a novel co-activator of YY1". J. Biol. Chem. 279 (17): 17750–5. doi:10.1074/jbc.M310532200. PMID 14744866.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163374 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11710830-3] Wang ZX, Wang HY, Wu MC (Nov 2001). "Identification and characterization of a novel human hepatocellular carcinoma-associated gene". Br J Cancer. 85 (8): 1162–7. doi:10.1054/bjoc.2001.2059. PMC 2375167. PMID 11710830.

[entrez-4] "Entrez Gene: YY1AP1 YY1 associated protein 1".

YY1AP1

References

Further reading