Yoshihiro Kawaoka
Yoshihiro Kawaoka (河岡 義裕, Kawaoka Yoshihiro, born November 14, 1955) is a virologist specializing in the study of the influenza and Ebola viruses. He holds a professorship in virology in the Department of Pathobiological Sciences at the University of Wisconsin-Madison, USA, and at the University of Tokyo, Japan.
Yoshihiro Kawaoka | |
|---|---|
| Born | November 14, 1955 Kobe, Japan |
| Alma mater | Hokkaido University |
| Occupation(s) | Virologist, professor at University of Wisconsin-Madison and University of Tokyo |
| Known for | Studies of influenza and Ebola viruses |
| Awards | Robert Koch Prize (2006) Carlos J. Finlay Prize for Microbiology (2015) Japan Academy Prize (2016) Keio Medical Science Prize (2022) |
Following the West African Ebola virus epidemic of 2014, Kawaoka began development of an Ebola vaccine working in close coordination with Alhaji N'jai a toxicologist at the University of Wisconsin–Madison and his non-profit organization Project 1808, Inc.[1]
Controversial experiment
Kawaoka reinvented a new virus based on H5N1, which he revealed to the public in 2011.[2] For now, no known vaccine has been found. His research was halted by a moratorium issued from the US government in 2014. However, in 2019 he was allowed to resume the research.[3][4]
Recognition
- 2006 – Robert Koch Prize (with Peter Palese)[6]
- 2011 – Medal with Purple Ribbon
- 2013 – Members of the United States National Academy of Sciences
- 2014 – Popular Mechanics Breakthrough Award
- 2015 – Carlos J. Finlay Prize for Microbiology
- 2016 – Japan Academy Prize
- 2018 – Sir Michael Stoker Prize[7]
- 2022 - Keio Medical Science Prize[8]
- 2023 - Person of Cultural Merit[9]
Selected publications
- Jasenosky, Luke D; Neumann, Gabriele; Lukashevich, Igor; Kawaoka, Y (2001-06-01). "Ebola virus vp40-induced particle formation and association with the lipid bilayer". J Virol. 75 (11): 5205–5214. doi:10.1128/JVI.75.11.5205-5214.2001. OCLC 6965132858. PMC 114926. PMID 11333902.
- Watanabe, Tokiko; Watanabe, Shinji; Ito, Hiroshi; Kida, Hiroshi; Kawaoka, Y (2001-06-15). "Influenza A virus can undergo multiple cycles of replication without m2 ion channel activity". J Virol. 75 (12): 5656–5662. doi:10.1128/jvi.75.12.5656-5662.2001. PMC 114278. PMID 11356973. Retrieved 2018-03-26.
- Schultz-Cherry, S; Dybdahl-Sissoko, N; Neumann, G; Kawaoka, Y; Hinshaw VS (2001-09-01). "Influenza Virus NS1 Protein Induces Apoptosis in Cultured Cells". J Virol. 75 (17): 7875–7881. doi:10.1128/jvi.75.17.7875-7881.2001. ISSN 0022-538X. OCLC 120974346. PMC 115031. PMID 11483732.
- Hatta, M; Gao, P; Halfmann, P; Kawaoka, Y (2001-09-07). "Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses". Science. 293 (298): 1840–1842. Bibcode:2001Sci...293.1840H. doi:10.1126/science.1062882. ISSN 0036-8075. OCLC 95118961. PMID 11546875. S2CID 37415902.
- Goto, Hideo; Wells, Krisna; Takada, Ayato; Kawaoka, Y. (2001-10-01). "Plasminogen-binding activity of neuraminidase determines the pathogenicity of influenza A virus". J Virol. 75 (19): 9297–9301. doi:10.1128/jvi.75.19.9297-9301.2001. ISSN 0022-538X. OCLC 6965138857. PMC 114497. PMID 11533192.
- Kobasa, Darwyn; Wells, Krisna; Kawaoka, Yoshihiro (2001-12-01). "Amino Acids Responsible for the Absolute Sialidase Activity of the Influenza A Virus Neuraminidase: Relationship to Growth in Duck Intestine". J Virol. 75 (23): 11773–11780. doi:10.1128/jvi.75.23.11773-11780.2001. OCLC 4639538185. PMC 114763. PMID 11689658.
- Kawaoka, Y; Neumann, Gabriele (2012). Influenza Virus : Methods and Protocols. Methods in Molecular Biology, Methods and Protocols, 865. Vol. 865. Springer. doi:10.1007/978-1-61779-621-0. ISBN 978-1-61779-620-3. S2CID 3687150.
- Watanabe, Tokiko; Kawaoka, Yoshihiro (June 2016). "Ebora shukketsu netsu no seiatsu ni mukete : Wakuchin kaihatsu to shierareone de no kenkyu" [Control of Ebola hemorrhagic fever : vaccine development and our Ebola project in Sierra Leone]. Virus (in Japanese). 66 (1): 53–62. doi:10.2222/jsv.66.53. ISBN 9781617796203. ISSN 0042-6857. OCLC 6807788600. PMID 28484179.
References
- "Project 1808".
- "Scientists Brace for Media Storm Around Controversial Flu Studies". 2011-11-24.
- "UW-Madison scientist allowed to resume controversial flu research | Local News | madison.com". 6 March 2019.
- "EXCLUSIVE: Controversial experiments that could make bird flu more risky poised to resume". 2019-02-09.
- Dan Burstein, Secrets of Inferno: In the Footsteps of Dante and Dan Brown. Story Plant, 2013.
- Robert-Koch-Stiftung: Robert Koch Award. Retrieved 4 July 2014.
- "Sir Michael Stoker Prize & Lecture 2018".
- "慶應医学賞受賞者一覧". 慶應義塾医学振興基金. Retrieved 2022-09-21.
- "塩野七生さんら7人文化勲章＝功労者に北大路欣也さんら". Jiji Press. Retrieved October 21, 2023.
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