Yosi, the Regretful Spy

• Natalia Oreiro as Claudia, Yosi's superior and only contact, she is a controlling and anti-Semitic agent, who believes in the Andinia Plan and seeks to prevent it from being carried out in Argentina.[7]
• Gustavo Bassani as José Pérez / Yosi, an anti-Semitic police intelligence agent who infiltrates a Jewish community.[8]
• Alejandro Awada as Saúl Menajem, a businessman linked to finance and banking, who traffics arms[9]
• Carla Quevedo as Eli, a committed young Jewish woman who is politically active and has a secret from the past that haunts her[10]
• Minerva Casero as Dafne Menajem, Saúl's daughter and Yosi's romantic interest[11]
• Juan Leyrado as Abraham Glusberg, the Jewish husband of José's mother
• Marco Antonio Caponi as Luis Garrido, José's friend and corrupt intelligence agent who conducts business outside the law.
• Daniel Kuzniecka as Aarón
• Matías Mayer as Víctor Kesselman, leader of the left-wing political group that Yosi joins.[12]

• Mirella Pascual as Zuni
• César Troncoso as Castaño
• Damián Dreizik as Marcelo
• Carlos Belloso as Kadar

• Roly Serrano as Minister Aquino
• Julián Ache Pérez Zinola as Jonás Kesselman
• Mercedes Morán as Mónica Raposo
• Danna Liberman as Silvina
• Miguel Di Lemme as Daniel Cruz
• Lucio Hernández as Salerno
• Víctor Wainbuch as Rabbi Straimel
• Fernando Miró as Prosecutor Castillo
• Roberto Suárez as Horacio Gutiérrez
• David Masajnik as Doctor Roitman

In February 2017, it was announced that the Argentine production company Oficina Burman had joined Mediapro to develop several projects to launch internationally, including the adaptation of the book Iosi, el espía arrepentido written by Horacio Lutzky and Miriam Lewin, and which tells the real story of an Argentine policeman who infiltrates a Jewish community.[13] In January 2020, Daniel Burman and Sebastián Borensztein were confirmed as the directors of the series that would be made up of 8 episodes of 40–50 minutes each.[14] On 7 April 2022, it was announced that the series would premiere on the 29th.[15] On 26 May 2022, Amazon Prime Video renewed the show for a second series.[16] In September 2023, the premiere of the second season was announced for October 27.[17]

On 17 May 2018, it was announced that Natalia Oreiro, Gustavo Bassani, Marco Antonio Caponi, Alejandro Awada, Juan Leyrado, Matías Mayer and Minerva Casero had joined the show's main cast. In January 2021, it was reported that Carla Quevedo had been cast.[18] At the end of May 2022, it was reported that two Israeli actors Moran Rosenblatt and Itzik Cohen would join the cast of the series.[19]

Filming for the first series took place at several locations in Uruguay during 2021.[20] Although the filming took place mainly in Montevideo, several towns in the Canelones Department, such as Progreso, Cerrillos, La Paz and Paso de Carrasco were also included.[21]

Raúl Kollmann of Página 12 gave a positive review and wrote: "Iosi, el espía arrepentido makes visible what that time was and what the infiltrators of the Federal Police were. But above all because the chapters are exciting, with a huge production that includes beautiful images in the desert, good performances and a rhythm that has nothing to envy to the best series".[22]