ZC3H12A

Zinc finger CCCH-type containing 12A is a protein in humans that is encoded by the ZC3H12A gene.[5]

ZC3H12A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesZC3H12A, MCPIP, MCPIP1, dJ423B22.1, zinc finger CCCH-type containing 12A, Reg1, MCPIP-1
External IDsOMIM: 610562 MGI: 2385891 HomoloGene: 11824 GeneCards: ZC3H12A
Orthologs
SpeciesHumanMouse
Entrez

80149

230738

Ensembl

ENSG00000163874

ENSMUSG00000042677

UniProt

Q5D1E8

Q5D1E7

RefSeq (mRNA)

NM_025079
NM_001323550
NM_001323551

NM_153159

RefSeq (protein)

NP_001310479
NP_001310480
NP_079355

NP_694799

Location (UCSC)Chr 1: 37.47 – 37.48 MbChr 4: 125.01 – 125.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.

References

  1. GRCh38: Ensembl release 89: ENSG00000163874 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000042677 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Zinc finger CCCH-type containing 12A".

Further reading


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