ZFYVE28

ZFYVE28
Identifiers
Aliases	ZFYVE28, LST2, LYST2, zinc finger FYVE-type containing 28, lst-2
External IDs	OMIM: 614176 MGI: 2684992 HomoloGene: 15119 GeneCards: ZFYVE28
Gene location (Human)
Chr.	Chromosome 4 (human)[1]
End	2,418,651 bp[1]
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)[2]
End	34,445,793 bp[2]
RNA expression pattern
	Top expressed in
	Brodmann area 9; ; nucleus accumbens; ; body of stomach; ; prefrontal cortex; ; anterior pituitary; ; caudate nucleus; ; right lobe of thyroid gland; ; sural nerve; ; left lobe of thyroid gland; ; postcentral gyrus;
	Top expressed in
	cerebellar cortex; ; superior frontal gyrus; ; cerebellar vermis; ; piriform cortex; ; olfactory tubercle; ; facial motor nucleus; ; nucleus accumbens; ; mirror; ; prefrontal cortex; ; spermatid;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; phosphatidylinositol-3-phosphate binding; metal ion binding;
Cellular component	cytoplasm; cytosol; endosome; early endosome membrane; membrane;
Biological process	negative regulation of epidermal growth factor-activated receptor activity; negative regulation of epidermal growth factor receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	57732
	231125
	ENSG00000159733
	ENSMUSG00000037224
	Q9HCC9
	Q6ZPK7
NM_001172656; NM_001172657; NM_001172658; NM_001172659; NM_001172660;
	NM_020972
	NM_001015039
NP_001166127; NP_001166128; NP_001166129; NP_001166130; NP_001166131;
	NP_066023
	NP_001015039
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger FYVE-type containing 28 is a protein that in humans is encoded by the ZFYVE28 gene. [5]

References

GRCh38: Ensembl release 89: ENSG00000159733 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000037224 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Zinc finger FYVE-type containing 28". Retrieved 2016-12-27.

Mosesson Y, Chetrit D, Schley L, Berghoff J, Ziv T, Carvalho S, Milanezi F, Admon A, Schmitt F, Ehrlich M, Yarden Y (2009). "Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling". Dev. Cell. 16 (5): 687–98. doi:10.1016/j.devcel.2009.03.015. PMC 3356849. PMID 19460345.

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