ZNRD1

DNA-directed RNA polymerase I subunit RPA12 is an enzyme that in humans is encoded by the ZNRD1 gene.[5][6][7]

POLR1H
Identifiers
AliasesPOLR1H, HTEX-6, Rpa12, TEX6, ZR14, hZR14, tctex-6, HTEX6, TCTEX6, zinc ribbon domain containing 1, RNA polymerase I subunit H, ZNRD1, A12.2
External IDsOMIM: 607525 MGI: 1913386 HomoloGene: 40960 GeneCards: POLR1H
Orthologs
SpeciesHumanMouse
Entrez

30834

66136

Ensembl

ENSMUSG00000036315

UniProt

Q9P1U0
Q2L6J2

Q791N7

RefSeq (mRNA)

NM_001278785
NM_001278786
NM_014596
NM_170783

NM_023162
NM_001355422

RefSeq (protein)

NP_075651
NP_001342351

Location (UCSC)Chr 6: 30.06 – 30.06 MbChr 17: 37.27 – 37.27 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I. Alternate splicing of this gene results in two transcript variants encoding the same protein. Additional splice variants have been described, but their full-length sequences have not been determined.[7]

References

  1. ENSG00000224859, ENSG00000235443, ENSG00000236949, ENSG00000235176, ENSG00000233795, ENSG00000236808, ENSG00000066379 GRCh38: Ensembl release 89: ENSG00000206502, ENSG00000224859, ENSG00000235443, ENSG00000236949, ENSG00000235176, ENSG00000233795, ENSG00000236808, ENSG00000066379 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000036315 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lepourcelet M, Andrieux N, Giffon T, Pichon L, Hampe A, Galibert F, Mosser J (Nov 1996). "Systematic sequencing of the human HLA-A/HLA-F region: establishment of a cosmid contig and identification of a new gene cluster within 37 kb of sequence". Genomics. 37 (3): 316–26. doi:10.1006/geno.1996.0566. PMID 8938444.
  6. Fan W, Wang Z, Kyzysztof F, Prange C, Lennon G (Jan 2000). "A new zinc ribbon gene (ZNRD1) is cloned from the human MHC class I region". Genomics. 63 (1): 139–41. doi:10.1006/geno.1999.6040. PMID 10662553.
  7. "Entrez Gene: ZNRD1 zinc ribbon domain containing 1".

Further reading

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