Zinc finger protein 197

ZNF197
Identifiers
Aliases	ZNF197, D3S1363E, P18, VHLaK, ZKSCAN9, ZNF166, ZNF20, ZSCAN41, zinc finger protein 197
External IDs	OMIM: 618359 HomoloGene: 48487 GeneCards: ZNF197
Gene location (Human)
Chr.	Chromosome 3 (human)[1]
End	44,648,471 bp[1]
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; Achilles tendon; ; corpus callosum; ; skeletal muscle tissue; ; islet of Langerhans; ; gastrocnemius muscle; ; endometrium; ; stromal cell of endometrium; ; smooth muscle tissue; ; sural nerve;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; intracellular anatomical structure;
Biological process	transcription, DNA-templated; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	10168
	n/a
	ENSG00000281709; ENSG00000186448
	n/a
	O14709
	n/a
NM_001024855; NM_001323293; NM_001323294; NM_001323295; NM_001323296;
	NM_006991
	n/a
NP_001020026; NP_001310222; NP_001310223; NP_001310224; NP_001310225;
	NP_008922
	n/a
	Wikidata
View/Edit Human

Zinc finger protein 197 is a protein that in humans is encoded by the ZNF197 gene. [3]

Function

This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Naturally-occurring readthrough transcription is observed between this gene and the upstream zinc finger protein 660 gene and is represented by GeneID:110354863.

References

ENSG00000186448 GRCh38: Ensembl release 89: ENSG00000281709, ENSG00000186448 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Zinc finger protein 197". Retrieved 2017-07-06.

Zinc finger protein 197

Function

References

Further reading