Adibendan

Adibendan is an inhibitor of phosphodiesterase 3. It has been tested in dogs for its effects on heart output and dilation of blood vessels.[1]

Adibendan
Names
Preferred IUPAC name
7,7-Dimethyl-2-(pyridin-4-yl)-5,7-dihydroimidazo[4,5-f]indol-6(1H)-one
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
UNII
InChI
  • InChI=1S/C16H14N4O/c1-16(2)10-7-12-13(8-11(10)20-15(16)21)19-14(18-12)9-3-5-17-6-4-9/h3-8H,1-2H3,(H,18,19)(H,20,21)
    Key: TVLQBBHUNDMTEC-UHFFFAOYSA-N
  • InChI=1/C16H14N4O/c1-16(2)10-7-12-13(8-11(10)20-15(16)21)19-14(18-12)9-3-5-17-6-4-9/h3-8H,1-2H3,(H,18,19)(H,20,21)
    Key: TVLQBBHUNDMTEC-UHFFFAOYAG
SMILES
  • CC1(C2=CC3=C(C=C2NC1=O)NC(=N3)C4=CC=NC=C4)C
Properties
Chemical formula
 C16H14N4O
Molar mass 278.315 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Dorszewski, A; Müller-Beckmann, B; Kling, L; Sponer, G (1990). "Haemodynamic profile of an inhibitor of phosphodiesterase III, adibendan (BM 14.478): Comparison with nitroprusside and dobutamine in conscious dogs". British Journal of Pharmacology. 101 (3): 686–90. doi:10.1111/j.1476-5381.1990.tb14141.x. PMC 1917742. PMID 2076485.


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