Adiphenine

Adiphenine is an inhibitor of nicotinic receptors.[1]

Adiphenine
Names
Preferred IUPAC name
2-(Diethylamino)ethyl diphenylacetate
Other names
Diphacil
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.000.545
EC Number
  • 200-599-0
KEGG
MeSH C084829
PubChem CID
UNII
InChI
  • InChI=1S/C20H25NO2/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14,19H,3-4,15-16H2,1-2H3
    Key: JGOAIQNSOGZNBX-UHFFFAOYSA-N
  • InChI=1/C20H25NO2/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14,19H,3-4,15-16H2,1-2H3
    Key: JGOAIQNSOGZNBX-UHFFFAOYAN
SMILES
  • CCN(CC)CCOC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2
Properties
Chemical formula
 C20H25NO2
Molar mass 311.425 g·mol−1
Melting point 112–114 °C (234–237 °F; 385–387 K)
Hazards
Lethal dose or concentration (LD, LC):
290 mg/kg (mouse; intraperitoneal)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References
  1. Spitzmaul, G; Gumilar, F; Dilger, JP; Bouzat, C (2009). "The local anaesthetics proadifen and adiphenine inhibit nicotinic receptors by different molecular mechanisms". British Journal of Pharmacology. 157 (5): 804–17. doi:10.1111/j.1476-5381.2009.00214.x. PMC 2721265. PMID 19422391.


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