Adosopine

Adosopine is a dibenzoazepine drug that has been studied for the treatment of urinary incontinence.[1][2]

Adosopine
Names
Preferred IUPAC name
N-(5-Methyl-6,11-dioxo-6,11-dihydro-5H-dibenzo[b,e]azepin-10-yl)acetamide
Other names
Adosupine
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.081.230
PubChem CID
UNII
InChI
  • InChI=1S/C17H14N2O3/c1-10(20)18-13-8-5-7-12-15(13)16(21)11-6-3-4-9-14(11)19(2)17(12)22/h3-9H,1-2H3,(H,18,20)
    Key: KLSKLNWJEDXFSD-UHFFFAOYSA-N
  • InChI=1/C17H14N2O3/c1-10(20)18-13-8-5-7-12-15(13)16(21)11-6-3-4-9-14(11)19(2)17(12)22/h3-9H,1-2H3,(H,18,20)
    Key: KLSKLNWJEDXFSD-UHFFFAOYAV
SMILES
  • CC(=O)NC1=CC=CC2=C1C(=O)C3=CC=CC=C3N(C2=O)C
Properties
Chemical formula
 C17H14N2O3
Molar mass 294.310 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References
  1. Perico, A; Triolo, A; Viti, G; Mannucci, C; Caviglioli, G; Cocchini, A; Pestellini, V; Paoli, P; Dapporto, P (1994). "Synthesis, characterization, and analytical studies of adosupine, a potential new drug for urinary incontinence". Journal of Pharmaceutical Sciences. 83 (2): 137–42. doi:10.1002/jps.2600830206. PMID 8169779.
  2. d'Aranno, V; Mancinelli, A; Manzini, S (1992). "Determination of the tricyclic compound adosupine and its three metabolites in plasma and brain of rat using high-performance liquid chromatography". Journal of Chromatography. 574 (2): 319–25. doi:10.1016/0378-4347(92)80046-s. PMID 1618966.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.