Adult-onset immunodeficiency syndrome

Adult-onset immunodeficiency syndrome is a provisional name for an immunodeficiency illness. The name is proposed in the first public study to identify the syndrome.[1] It appears to be chronic and non-contagious, affecting mainly people of Asian descent aged around 50.[2][3] Cases first started appearing in 2004, primarily in Thailand and Taiwan.

Adult-onset immunodeficiency syndrome
Other namesAdult-onset immunodeficiency with anti-interferon-gamma autoantibodies

Signs and symptoms

At least one physician associates the symptoms with tuberculosis. Some lethal overwhelming infections are reported, aggravating people who already suffer other conditions such as HIV/AIDS.

Cause

Little is publicly known about the underlying factors causing the disease. Genetic factors are suspected, but the disease does not appear to be heritable. Also, something in the environment may trigger the disease.

Mechanism

An elevated concentration of autoantibodies that block interferon-gamma was detected in most patients.

Society and culture

The swash.com website uses AIDS 2.0 as the moniker for maybe another, apparently highly contagious AIDS-like condition described by The Epoch Times.[4]

The Daily Beast has described this disease emphatically as not AIDS 2.0.[5]

References
  1. Browne, S. K.; Burbelo, P. D.; Chetchotisakd, P.; Suputtamongkol, Y.; Kiertiburanakul, S.; Shaw, P. A.; Kirk, J. L.; Jutivorakool, K.; Zaman, R.; Ding, L.; Hsu, A. P.; Patel, S. Y.; Olivier, K. N.; Lulitanond, V.; Mootsikapun, P.; Anunnatsiri, S.; Angkasekwinai, N.; Sathapatayavongs, B.; Hsueh, P. R.; Shieh, C. C.; Brown, M. R.; Thongnoppakhun, W.; Claypool, R.; Sampaio, E. P.; Thepthai, C.; Waywa, D.; Dacombe, C.; Reizes, Y.; Zelazny, A. M.; Saleeb, P. (2012). "Adult-Onset Immunodeficiency in Thailand and Taiwan". New England Journal of Medicine. 367 (8): 725–734. doi:10.1056/NEJMoa1111160. PMC 4190026. PMID 22913682.
  2. Marilynn Marchione (2012-08-22). "New immune-system disease found in Asians; causes AIDS-like symptoms in people without HIV". The Washington Post. Archived from the original on 2012-08-27. Retrieved 26 August 2012.
  3. "New AIDS-like mystery disease". The Voice of Russia. 2012-08-22. Archived from the original on 25 August 2012. Retrieved 26 August 2012.
  4. "AIDS 2.0: Highly contagious disease spreading in China". The Swash. 2012-08-22. Retrieved 26 August 2012.
  5. Kent Sepkowitz (2012-08-22). "New Thai-Taiwanese Syndrome Is Not AIDS 2.0". The Daily Beast. Retrieved 26 August 2012.


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