Alimentary toxic aleukia

Alimentary toxic aleukia
Alimentary toxic aleukia
Other names	Aleukia

Alimentary toxic aleukia is a mycotoxin-induced condition characterized by nausea, vomiting, diarrhea, leukopenia (aleukia), hemorrhaging, skin inflammation, and sometimes death.[1] Alimentary toxic aleukia almost always refers to the human condition associated with presence of T-2 toxin.

History

Alimentary toxic aleukia was first characterized in the early 20th century after affecting a large population in the Orenburg Oblast of the former USSR during World War II. The sick people had eaten overwintered grain colonized with Fusarium sporotrichioides and Fusarium poae.[2]

References

Lutsky, II; Mor, N (1981). "Alimentary toxic aleukia (septic angina, endemic panmyelotoxicosis, alimentary hemorrhagic aleukia): t-2 toxin-induced intoxication of cats". Am J Pathol. 104 (2): 189–91. PMC 1903757. PMID 6973281.
Bennett, JW; Klich, M (July 2003). "Mycotoxins". Clin. Microbiol. Rev. 16 (3): 497–516. doi:10.1128/cmr.16.3.497-516.2003. PMC 164220. PMID 12857779.

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[1] Lutsky, II; Mor, N (1981). "Alimentary toxic aleukia (septic angina, endemic panmyelotoxicosis, alimentary hemorrhagic aleukia): t-2 toxin-induced intoxication of cats". Am J Pathol. 104 (2): 189–91. PMC 1903757. PMID 6973281.

[2] Bennett, JW; Klich, M (July 2003). "Mycotoxins". Clin. Microbiol. Rev. 16 (3): 497–516. doi:10.1128/cmr.16.3.497-516.2003. PMC 164220. PMID 12857779.