Ambucetamide

Ambucetamide is an antispasmodic found to be particularly effective for the relief of menstrual pain. It was discovered in 1953 by Paul Janssen.

Ambucetamide
Clinical data
ATC code
  • none
Identifiers
IUPAC name
  • 2-(dibutylamino)-2-(4-methoxyphenyl)acetamide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.007.527
Chemical and physical data
FormulaC17H28N2O2
Molar mass292.423 g·mol−1
3D model (JSmol)
SMILES
  • O=C(N)C(c1ccc(OC)cc1)N(CCCC)CCCC
InChI
  • InChI=1S/C17H28N2O2/c1-4-6-12-19(13-7-5-2)16(17(18)20)14-8-10-15(21-3)11-9-14/h8-11,16H,4-7,12-13H2,1-3H3,(H2,18,20) Y
  • Key:WUSAVCGXMSWMQM-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

References

    • Hoekstra JB, Fisher DS, Cull KM, Tisch DE, Dickison HL., Studies with a uterine antispasmodic, ambucetamide, J Am Pharm Assoc Am Pharm Assoc (Baltim). 1957 Sep;46(9):564-8.
    • Pickles VR, Clitheroe HJ., The effects of ambucetamide on human myometrial and other preparations, and its antagonism to the menstrual stimulant, Br J Pharmacol Chemother. 1960 Mar;15:128-30.


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