Amorphous globosus

Amorphus globosus (from Greek: αμορφή (amorphē) 'formless' and Latin: globus 'sphere') is a malformation occurring in veterinary medicine, especially in domestic cattle. Instead of a normally developed fetus, it results in the formation of a more or less spherical structure covered with hairy skin, which contains parts of all three germ layers; the differentiation of its contents can vary greatly. An amorphus globosus is not viable due to the lack of functional organs.

An Amorphous Globosus

Origin

The teratological reasons for the development of amorphus globosus are not fully understood, but it is believed that The malformation is generally associated with twin gestation, in which one embryo does not develop normally. In two cases, the karyotype of the amorphus was identical to its normally developing twin,[1][2] while in another case, the karotype deviated from the normal twin,[3] so that an emergence from fraternal twins also seems possible.

Distribution

Amorphus globosus is more common in livestock than generally assumed.[4] It occurs most commonly in cattle, but there are also case reports in goats,[4] and Horses.[5] A case of Amorphus globosus has also been described in human medicine, where it was also a twin pregnancy.[6]

References
  1. M. Hishinuma, Y. Takahashi, H. Kanagawa: Histological and cytological observation on a bovine acardius amorphus. In: Jpn J Vet Sci. 49, 1987, S. 195–197.
  2. S. Kamimura, S. Enomoto, K. Goto, K. Hamana: A Globosus amorphus from an in vitro fertilized embryo transferred to a Japanese black cow. In: Theriogenology. Band 40, Nummer 4, Oktober 1993, S. 853–858, ISSN 0093-691X. PMID 16727366.
  3. M. Hishinuma, N. Hoshi, Y. Takahashi, H. Kanagawa: Vasculature and chromosomal composition in a bovine acardius amorphus. In: Nihon juigaku zasshi. The Japanese journal of veterinary science. Band 50, Nummer 5, Oktober 1988, S. 1139–1141, ISSN 0021-5295. PMID 3199627.
  4. M. T. Anwar, A. I. Khan, S. Balasubramanian, R. Jayaprakash, T. A. Kannan, S. Manokaran, S. A. Asokan, C. Veerapandian: A rare case of globosus amorphus in a goat. In: The Canadian veterinary journal. La revue vétérinaire canadienne. Band 50, Nummer 8, August 2009, S. 854–856, ISSN 0008-5286. PMID 19881925. PMC 2711472.
  5. P. J. Crossman, P. S. Dickens: Amorphus globosus in the mare. In: The Veterinary record. Band 95, Nummer 1, Juli 1974, S. 22, ISSN 0042-4900. PMID 4432366.
  6. T. Maggiora-Vergano, G. Gentile: [A case of amorphous twin: holocardius amorphous globosus]. In: La Clinica ostetrica e ginecologica. Band 56, Nummer 4, August 1954, S. 235–244, ISSN 0393-9227. PMID 13231331.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.