Bromofenofos

Bromofenofos is an anthelminthic agent used in veterinary medicine. It is used to treat common liver fluke (Fasciola hepatica) infections in cattle and sheep.[1][2]

Bromofenofos
Clinical data
Trade namesAcedist
Other namesBromfenofos; Bromophenophos; Bromphenophos; Bromophenfos
ATCvet code
Identifiers
IUPAC name
  • 3,3',5,5'-Tetrabromo-2'-hydroxy-2-biphenylyl dihydrogen phosphate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.040.349
Chemical and physical data
FormulaC12H7Br4O5P
Molar mass581.773 g·mol−1
3D model (JSmol)
SMILES
  • C1=C(C=C(C(=C1Br)O)C2=CC(=CC(=C2OP(=O)(O)O)Br)Br)Br
InChI
  • InChI=1S/C12H7Br4O5P/c13-5-1-7(11(17)9(15)3-5)8-2-6(14)4-10(16)12(8)21-22(18,19)20/h1-4,17H,(H2,18,19,20)
  • Key:MMYHZEDBTMXYAF-UHFFFAOYSA-N

It is teratogenic.[3][4]

References

  1. Studdert VP, Gay CC, Blood DC (2011). Saunders Comprehensive Veterinary Dictionary. Elsevier Health Sciences.
  2. Ruckebusch Y, Toutian PL, Koritz GD, eds. (2012). Veterinary Pharmacology and Toxicology. Springer Science & Business Media. p. 762.
  3. Shepard TH, Lemire RJ (2004). Catalog of Teratogenic Agents. JHU Press. p. 52.
  4. Yoshimura H (June 1987). "Comparative embryolethal effect of bromofenofos and dephosphate bromofenofos in rats". Archives of Toxicology. 60 (4): 325–7. doi:10.1007/BF01234673. PMID 2820352. S2CID 21143121.
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